CuI/MnO2 nanocatalysed synthesis of bioactive 2-substituted benzimidazoles

被引：0

作者：

Nisha ^{[1
]}

Kohli, Sahil ^{[2
]}

Aggarwal, Khushboo ^{[1
]}

Singh, Snigdha ^{[1
]}

Sharma, Neera ^{[3
]}

Chandra, Ramesh ^{[1
,4
,5
,6
]}

机构：

[1] Univ Delhi, Dept Chem, Drug Discovery & Dev Lab, Delhi 110007, India

[2] Manav Rachna Int Inst Res & Studies, Sch Engn & Technol, Dept Chem, Faridabad 121004, Haryana, India

[3] Univ Delhi, Hindu Coll, Dept Chem, Delhi 110019, India

[4] Univ Delhi, Dr BR Ambedkar Ctr Biomed Res ACBR, Delhi 110007, India

[5] Univ Delhi, Inst Nanomed Sci INMS, Delhi 110007, India

[6] Maharaja Surajmal Brij Univ, Bharatpur 321201, Rajasthan, India

来源：

INORGANIC CHEMISTRY COMMUNICATIONS | 2025年 / 171卷

关键词：

Nanocomposite; Catalyst; Benzimidazoles; Copper iodide; CROSS-COUPLING REACTIONS; COPPER NANOPARTICLES; ASSISTED SYNTHESIS; REUSABLE CATALYST; CLICK CHEMISTRY; EFFICIENT; DERIVATIVES; TETRAZOLES; ARYLATION; COMPLEX;

D O I：

10.1016/j.inoche.2024.113556

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

This work focusses on the development and characterization of efficient CuI/MnO2 nano catalyst, characterized using XPS, XRD, EDAX, FTIR, FESEM, BET (surface area: 8.01 m2/g, a pore radius: 17.052 & Aring; and a pore volume: 0.011 cm3/g) and TEM techniques. The reactivity of this catalyst was evaluated for the synthesis of biologically active 2-substituted benzimidazoles through condensation of o-phenylenediamine with benzaldehydes. The process features short reaction time, high TON (997.35), green conditions, high yield, easy work-up, good green metrices values such as low E-factor (0.17) and Process mass efficiency (PMI) (1.16) high Reaction mass efficiency (RME) value (91.2 %) and carbon efficiency (CE) (94 %) are good characteristics of the synthesized catalyst.

引用

页数：8

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