Surface plasmon resonance biosensors and their medical applications

被引：0
|
作者：
Springer, Tomas [1 ]
Bockova, Marketa [1 ]
Slaby, Jiri [1 ]
Sohrabi, Foozieh [1 ]
Capkova, Magdalena [1 ]
Homola, Jiri [1 ]
机构：
[1] Czech Acad Sci, Inst Photon & Elect, Chaberska 1014-57, Prague 18251, Czech Republic
来源：
BIOSENSORS & BIOELECTRONICS | 2025年 / 278卷
关键词：
Surface plasmon resonance biosensor; Plasmonic affinity biosensor; Optical biosensor; Medical diagnostics; Biomarker; LABEL-FREE DETECTION; NANOPLASMONIC BIOSENSOR; BLOOD; ENHANCEMENT; SENSORS; PROTEIN; ASSAY;
D O I：
10.1016/j.bios.2025.117308
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
Surface plasmon resonance (SPR) biosensors are an advanced optical biosensing technology that has been widely used in molecular biology for the investigation of biomolecular interactions and in bioanalytics for the detection of biological species. This work aims to review progress in the development of SPR biosensors for medical diagnostics, focusing mainly on advances in optical platforms and assays enabling analysis of complex biological matrices. Applications of SPR biosensors for the detection of medically relevant analytes, such as nucleic acids, proteins, exosomes, viruses, bacteria, and circulating tumor cells, are also reviewed. The detection performance of current SPR biosensors is discussed, and routes for improving performance and expanding applications of SPR biosensors in medical diagnostics are outlined.
引用
收藏
页数：15
相关论文
共 50 条
  • [31] Surface plasmon resonance biosensors with subwavelength grating waveguide
    Lin, C. -Y.
    Chien, F. -C.
    Yu, L. -Y.
    Chang, C. -W.
    Chiu, K. -C.
    Chen, S. -J.
    PLASMONICS IN BIOLOGY AND MEDICINE IV, 2007, 6450
  • [32] Review of Biosensors Based on Surface Plasmon Resonance br
    Shen, Changyu
    Sui, Wenbo
    Jun, Zhou
    Wei, Han
    Jie, Dong
    Bin, Fang
    Wang, Zhaokun
    LASER & OPTOELECTRONICS PROGRESS, 2023, 60 (11)
  • [33] Optical surface plasmon resonance biosensors in molecular fishing
    Ivanov A.S.
    Medvedev A.E.
    Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry, 2016, 10 (1) : 55 - 62
  • [34] Surface Plasmon Resonance Biosensors: Sensor Response Modeling
    Caglayan, Mustafa Oguzhan
    Atar, Necip
    Ustundag, Zafer
    JOURNAL OF COMPUTATIONAL AND THEORETICAL NANOSCIENCE, 2013, 10 (05) : 1248 - 1251
  • [35] Imaging differential phase surface plasmon resonance biosensors
    Ho, H. P.
    Wong, C. L.
    2006 IEEE LEOS ANNUAL MEETING CONFERENCE PROCEEDINGS, VOLS 1 AND 2, 2006, : 675 - +
  • [36] Cancer Biomarker Detection by Surface Plasmon Resonance Biosensors
    Reddy, Panga Jaipal
    Sadhu, Sudipta
    Ray, Sandipan
    Srivastava, Sanjeeva
    CLINICS IN LABORATORY MEDICINE, 2012, 32 (01) : 47 - +
  • [37] Molecular Scale Origin of Surface Plasmon Resonance Biosensors
    Yu, Hui
    Shan, Xiaonan
    Wang, Shaopeng
    Chen, Hongyuan
    Tao, Nongjian
    ANALYTICAL CHEMISTRY, 2014, 86 (18) : 8992 - 8997
  • [38] Surface plasmon resonance biosensors as a tool in antibody engineering
    Alfthan, K
    BIOSENSORS & BIOELECTRONICS, 1998, 13 (06): : 653 - 663
  • [39] Multichannel detector system for surface plasmon resonance biosensors
    Fernandes, M.
    Fantoni, A.
    Soares, P.
    Lourenco, P.
    Vieira, M.
    OPTICAL FIBERS AND SENSORS FOR MEDICAL DIAGNOSTICS, TREATMENT AND ENVIRONMENTAL APPLICATIONS XXII, 2022, 11953
  • [40] Surface Plasmon Resonance Biosensors Incorporating Gold Nanoparticles
    Bedford, Erin E.
    Spadavecchia, Jolanda
    Pradier, Claire-Marie
    Gu, Frank X.
    MACROMOLECULAR BIOSCIENCE, 2012, 12 (06) : 724 - 739
12345