Peri-Implant Epstein-Barr Virus (+) Mucocutaneous Ulcer in an Immunocompetent Patient: Case Report and Review of the Literature

被引：0

作者：

de Mendoza, Irene Lafuente-Ibanez ^{[1
]}

Aguirre-Echevarria, Pablo ^{[2
]}

Silva-Soria, Tulio Mateo ^{[2
]}

Aisa, Francisco Javier Vallejo ^{[3
]}

de Larrinoa, Aitor Fernandez ^{[4
]}

Aguirre-Urizar, Jose Manuel ^{[1
]}

机构：

[1] Univ Basque Country EHU, Dept Stomatol, Res Grp GIU21 042, Leioa, Spain

[2] Univ Basque Country EHU, Donostia Univ Hosp Osakidetza, Pathol Anat Serv, Donostia San Sebastian, Spain

[3] Moyua Dent Clin, Feder Moyua Plaza, Bilbao, Spain

[4] Univ Basque Country EHU, Cruces Univ Hosp Osakidetza, Pathol Anat Serv, Baracaldo, Spain

来源：

CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH | 2025年 / 27卷 / 01期

关键词：

case report; histological analysis; implant;

D O I：

10.1111/cid.13440

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Epstein-Barr virus (+) mucocutaneous ulcer (EBVMCU) is an uncommon benign lymphoproliferative lesion that develops in immunocompromised patients. We present a special case of EBVMCU located in the peri-implant mucosa and we review the oral cases published to date. An 88-year-old man with no medical history of interest was attended in the dental clinic due to an ulcerated tumor located in the peri-implant mucosa. The lesion showed an atypical lymphoid proliferation, positive for CD3, CD20, CD30, PAX-5, and MUM1. Positive EBV and favorable patient evolution confirmed the final diagnosis of EBVMCU. Oral EBVMCU reports related to immunosenescence mainly develop in the gingiva of advanced age patients. Our case highlights the importance to perform a complete clinicopathological study of all peri-implant lesions. Although most peri-implant pathologies are inflammatory-reactive disorders, sometimes they can also correspond to other entities.

引用

页数：5

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