Effects of physical exercise on the lipid profile of perimenopausal and postmenopausal women: a systematic review and meta-analysis

被引：0
作者：
Bernal, J. V. M. [1 ]
Sanchez-Delgado, J. C. [3 ]
Jacome-Hortua, A. M. [2 ]
Veiga, A. C. [1 ]
Andrade, G. V. [1 ]
Rodrigues, M. R. [1 ]
de Souza, H. C. D. [1 ]
机构：
[1] Univ Sao Paulo, Fac Med Ribeirao Preto, Dept Ciencia Saude, Lab Fisiol Exercicio & Fisioterapia Cardiovasc, Ribeirao Preto, SP, Brazil
[2] Univ Santander, Fac Ciencias Med & Salud, Bucaramanga, Colombia
[3] Univ Santo Tomas Bucaramanga, Fac Salud, Grp Invest Ser Cultura & Movimiento, Santander, Colombia
来源：
BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH | 2025年 / 58卷
基金：
巴西圣保罗研究基金会;
关键词：
Exercise; Secondary prevention; Review; Lipids; Climacteric; Menopause; METABOLIC SYNDROME FACTORS; AEROBIC EXERCISE; PHYSIOTHERAPY EVIDENCE; LIPOPROTEIN-LIPASE; SERUM ADIPONECTIN; BODY-COMPOSITION; WALKING PROGRAM; CHOLESTEROL; HEALTH; RISK;
D O I：
10.1590/1414-431X2025e14194
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
During the climacteric period, the decline in ovarian hormones leads to changes in the lipid profile. Physical exercise is the main non-pharmacological recommendation for controlling lipid levels. However, the effects on the lipid profile in perimenopausal and postmenopausal women are incipient and inconclusive. In this context, we searched the Embase, PubMed, Scopus, and Web of Science databases for randomized clinical trials on the effects of exercise on the lipid profile of these women. We excluded studies that did not specify criteria for classifying the climacteric phase, that involved women undergoing hormone replacement therapy, or that examined combined treatments or acute effects of physical exercise. The meta-analysis indicated that general physical exercise increased high-density lipoprotein cholesterol (HDL-C) levels (mean difference [MD]=4.89; 95% confidence interval [95%CI]=0.97 to 8.81) in perimenopausal women. For obese postmenopausal women, 16 weeks of aerobic training increased HDL-C levels (MD=3.88; 95%CI=0.56 to 7.20) and reduced total cholesterol (MD=-22.36; 95%CI=-29.67 to -15.05) and low-density lipoprotein cholesterol (LDL-C) levels (MD=-17.86; 95%CI=-25.97 to -9.75), whereas 12 weeks of resistance training increased HDL-C levels (MD=4.20; 95%CI=1.16 to 7.23) and decreased triglycerides (MD=-14.86; 95%CI=-26.62 to -3.09) and LDL-C levels (MD=-16.36; 95%CI=-28.05 to -4.67). Overall, the results showed that physical exercise regulated lipid profiles in perimenopausal and postmenopausal women. Specifically, 12 weeks of resistance exercise and 16 weeks of aerobic exercise improved the lipid profile of obese postmenopausal women.
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页数：13
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