Autophagy-dependent ferroptosis mediates multiple sclerosis

被引：2

作者：

Tang, Daolin ^{[1
]}

Kang, Rui ^{[1
]}

Klionsky, Daniel J. ^{[2
,3
]}

机构：

[1] UT Southwestern Med Ctr, Dept Surg, Dallas, TX 75390 USA

[2] Univ Michigan, Life Sci Inst, Ann Arbor, MI 48109 USA

[3] Univ Michigan, Dept Mol Cellular & Dev Biol, Ann Arbor, MI USA

来源：

AUTOPHAGY | 2025年 / 21卷 / 02期

基金：

美国国家卫生研究院;

关键词：

Cell death; GPX4; macroautophagy; neurons; STING1;

D O I：

10.1080/15548627.2024.2419112

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

A recent paper published in Cell by Woo et al. reported that autophagy-dependent ferroptosis mediated by STING1 is involved in neuronal death associated with multiple sclerosis (MS). This research broadens our understanding of the pathogenesis of MS and opens new avenues for therapeutic interventions.

引用

页码：257 / 259

页数：3

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