Fractals are geometric patterns that appear self-similar across all length scales and are constructed by repeating a single unit on a regular basis. Entropy, as a core thermodynamic function, is an extension based on information theory (such as Shannon entropy) that is used to describe the topological structural complexity or degree of disorder in networks. Topological indices, as graph invariants, provide quantitative descriptors for characterizing global structural properties. In this paper, we investigate two types of generalized Sierpi & nacute;ski graphs constructed on the basis of different seed graphs, and employ six topological indices-the first Zagreb index, the second Zagreb index, the forgotten index, the augmented Zagreb index, the Sombor index, and the elliptic Sombor index-to analyze the corresponding entropy. We utilize the method of edge partition based on vertex degrees and derive analytical formulations for the first Zagreb entropy, the second Zagreb entropy, the forgotten entropy, the augmented Zagreb entropy, the Sombor entropy, and the elliptic Sombor entropy. This research approach, which integrates entropy with Sierpi & nacute;ski network characteristics, furnishes novel perspectives and instrumental tools for addressing challenges in chemical graph theory, computer networks, and other related fields.