Factors associated with quality of life of chronic spontaneous urticaria patients in a Vietnamese population

被引:0
|
作者
Nguyen Thi Tra My [1 ,2 ]
Le Huyen My [3 ]
Vu Nguyet Minh [1 ,3 ]
Nguyen Thi Ha Vinh [1 ,3 ]
Mai Ba Hoang Anh [2 ]
Doanh Le Huu [1 ,3 ]
机构
[1] Hanoi Med Univ, Dept Dermatol, Hanoi, Vietnam
[2] Hue Univ Med & Pharm, Dept Dermatol, Hue, Vietnam
[3] Natl Dermatol & Venereol Hosp, Hanoi, Vietnam
来源
PLOS ONE | 2025年 / 20卷 / 01期
关键词
IMPACT; VERSION;
D O I
10.1371/journal.pone.0317499
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Objective Chronic spontaneous urticaria (CSU) is a challenging condition that significantly impacts the affected patients. This study aimed to evaluate the quality of life (QoL) among patients with CSU in Vietnam and identify factors associated with QoL. Methods A cross-sectional study was conducted at the Vietnam National Dermatology and Venereology Hospital from June 2023 to March 2024. A total of 358 CSU patients aged 16 years or older were recruited. Data were collected using a structured questionnaire covering demographic, clinical, and laboratory characteristics. The Chronic Urticaria Quality of Life Questionnaire (CU-Q(2)oL) and the Weekly Urticaria Activity Score (UAS7) were utilized to assess QoL and disease severity. Multivariate Tobit regression models were performed. Results The CU-Q(2)oL total score had a mean of 48.67 (SD = 16.90) and a median of 46 (IQR = 35-59). The scores for individual CU-QoL subscales were as follows: pruritus (5.422.02), swelling (2.86 +/- 1.54), life activities (13.89 +/- 6.00), sleep problems (11.12 +/- 4.96), limits (6.52 +/- 2.66), and looks (8.85 +/- 4.09). Higher UAS7 scores were associated with lower QoL, and angioedema in the eyes and lips were associated with increased swelling domain and poorer overall QoL. Longer disease duration was associated with higher pruritus scores, while a history of allergy was related to poorer total QoL, sleep, and looks. Severe itching further degraded sleep quality. Positive Autologous Serum Skin Test (ASST) was correlated with lower overall QoL, particularly in swelling and limits domains. Positive Basophil Histamine Release Assay (BHRA) status was linked to poorer sleep quality domain. Conclusion CSU significantly impairs the QoL of patients, affecting physical, emotional, and social dimensions. Regular QoL assessments should be integrated into clinical practice to ensure comprehensive and patient-centered treatment strategies.
引用
收藏
页数:14
相关论文
共 50 条
  • [1] Prevalence of Inducible Urticaria in Patients with Chronic Spontaneous Urticaria: Associated Risk Factors
    Sanchez, Jorge
    Amaya, Emerson
    Acevedo, Ana
    Celis, Ana
    Caraballo, Domingo
    Cardona, Ricardo
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, 2017, 5 (02): : 464 - 470
  • [2] Dupilumab Improves Urticaria Activity And Quality Of Life In Patients With Chronic Spontaneous Urticaria (CSU)
    Maurer, Marcus
    Casale, Thomas
    Saini, Sarbjot
    Ben-Shoshan, Moshe
    Radin, Allen
    Akinlade, Bolanle
    Fan, Chunpeng
    Bauer, Deborah
    Laws, Elizabeth
    Thomas, Ryan
    Mannent, Leda
    Stjepanovic, Aleksandra
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2023, 151 (02) : AB98 - AB98
  • [3] Remibrutinib Treatment Improves Quality of Life in Patients with Chronic Spontaneous Urticaria
    Maurer, Marcus
    Gimenez-Arnau, Ana
    Jain, Vipul
    Tillinghast, Jeffrey
    Tolcachier, Alberto
    Nigen, Simon
    Hayam, Koremasa
    Lheritier, Karine
    Walsh, Pauline
    Haemmerle, Sibylle
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2022, 149 (02) : AB179 - AB179
  • [4] Does angioedema influence the quality of life in patients with chronic spontaneous urticaria?
    Oles-Krykowska, A.
    Badura-Brzoza, K.
    Brzoza, Z.
    ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, 2019, 122 (05) : 539 - 541
  • [5] Dupilumab Improves Urticaria Signs and Symptoms and Quality of Life in Patients With Chronic Spontaneous Urticaria (CSU)
    Maurer, Marcus
    Casale, Thomas B.
    Saini, Sarbjit S.
    Ben-Shoshan, Moshe
    Radin, Allen
    Bauer, Deborah
    Thomas, Ryan B.
    Mannent, Leda P.
    Stjepanovic, Aleksandra
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2023, 89 (03) : AB40 - AB40
  • [6] Chronic Spontaneous Urticaria Quality of Life and Economic Impacts
    Keller, Levi
    Stitt, Jenny
    IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA, 2024, 44 (03) : 453 - 467
  • [7] Sleep quality in patients with chronic spontaneous urticaria
    Etgu, Fatma
    Onder, Sevda
    TURKDERM-TURKISH ARCHIVES OF DERMATOLOGY AND VENEROLOGY, 2023, 57 (02): : 55 - 60
  • [8] Quality of life in patients with chronic urticaria
    Ghaffari, J.
    Yazdanicharati, J.
    Zamanfar, D.
    Sadogh, A.
    ALLERGY, 2014, 69 : 558 - 558
  • [9] Quality of Life, Disease Burden and subjective Symptoms of Patients with chronic spontaneous Urticaria
    Langenbruch, A.
    Kressel, N.
    Braun, V
    Maurer, M.
    Reich, K.
    Augustin, M.
    JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, 2017, 15 : 113 - 114
  • [10] Chronic Spontaneous Urticaria: How to Assess Quality of Life in Patients Receiving Treatment
    Weller, Karsten
    Church, Martin K.
    Kalogeromitros, Dimitrios
    Krause, Karoline
    Magerl, Markus
    Metz, Martin
    Pisarevskaja, Dina
    Siebenhaar, Frank
    Maurer, Marcus
    ARCHIVES OF DERMATOLOGY, 2011, 147 (10) : 1221 - 1223