Asymmetric cyclopropanation via an electro-organocatalytic cascade

被引：2

作者：

Krech, Anastasiya ^{[1
]}

Laktsevich-Iskryk, Marharyta ^{[1
]}

Deil, Nora ^{[1
]}

Fokin, Mihhail ^{[1
]}

Kimm, Mariliis ^{[1
]}

Oseka, Maksim ^{[1
]}

机构：

[1] Tallinn Univ Technol, Dept Chem & Biotechnol, Akad Tee 15, Tallinn 12618, Estonia

来源：

CHEMICAL COMMUNICATIONS | 2024年 / 60卷 / 95期

关键词：

ENANTIOSELECTIVE CYCLOPROPANATION; ALKYLATION REACTIONS; METAL CATALYSIS; ALDEHYDES; RING;

D O I：

10.1039/d4cc05092d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report an iminium ion-promoted, asymmetric synthesis of cyclopropanes via an electrocatalytic, iodine-mediated ring closure. The mild, controlled electrochemical generation of electrophilic iodine species in catalytic quantities prevents organocatalyst deactivation, while also eliminating the need for halogenating reagents, thus simplifying traditional synthetic approaches.

引用

页码：14026 / 14029

页数：5

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