Evaluation of radiation treatment plan quality in head and neck cancer: a comparative analysis of RapidArc technique with flattening filter and flattening filter-free photon beams

被引：0
作者：
Mishra, Atul [1 ]
Manna, Sumanta [2 ]
Mittal, Kailash Kumar [1 ]
Singh, Sharad [2 ]
Yadav, Neha [3 ]
机构：
[1] Uttar Pradesh Univ Med Sci, Dept Radiat Oncol, Etawah 206130, Uttar Pradesh, India
[2] Kalyan Singh Super Specialty Canc Inst, Dept Radiat Oncol, Lucknow 226002, Uttar Pradesh, India
[3] Apollomed Super Special Hosp, Dept Radiat Oncol, Lucknow 226012, Uttar Pradesh, India
来源：
ECANCERMEDICALSCIENCE | 2025年 / 19卷
关键词：
intensity modulated; linear accelerator; radiotherapy; photons; radiotherapy plan- ning; conformal; FFF; FF; RapidArc; MODULATED ARC THERAPY; IMRT; RADIOTHERAPY; ESOPHAGEAL; VMAT;
D O I：
10.3332/ecancer.2025.1854
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Aim: This study aims to evaluate the treatment plan quality for oral cavity cancers in the head and neck region using the RapidArc (RA) technique with both flattening filter (FF) and flattening filter-free (FFF) photon beams. Materials and methods: In this analytical study, treatment plans for 12 patients originally planned with a 6 MV FF photon beam were recreated using the RA technique with a 6 MV FFF photon beam. Identical beam parameters and planning objectives were maintained for both sets of plans to facilitate comparison. All plans were evaluated based on planning indices and doses to organs at risk (OAR). Results: A significant dose variation was found in the minimum (Dmin) and mean (Dmean) doses of the high-risk planning target volume between FF and FFF photon beam RA plans. However, the dose distribution for the low-risk planning target volume was equivalent between the two techniques. The FFF-RA plans demonstrated superior conformity and homogeneity indices compared to the FF plans, with these differences being statistically significant. In addition, the FF-RA plans showed higher doses to the parotid glands, eyes and lenses than the FFF plans. The FFF plans also showed significantly shorter beam-on treatment times and a higher gamma passing index rate compared to the FF plans. Conclusion: In contrast to the FF photon beam, an FFF photon beam-oriented RA plan provides significant OAR sparing without losing the quality of the treatment plan. High monitor units and beam on time are major highlights of the RA plan with FFF beam.
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页数：12
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