Associations between people experiencing homelessness (PEH) and neurodegenerative disorders (NDDs): A systematic review and meta-analysis

被引:0
作者
Fu, Pengfei [1 ]
Mago, Vijay [1 ]
Schiff, Rebecca [2 ]
Krysowaty, Bonnie [3 ]
机构
[1] York Univ, Fac Hlth, Sch Hlth Policy & Management, Toronto, ON, Canada
[2] Univ Lethbridge, Lethbridge, AB, Canada
[3] Lakehead Social Planning Council, Victoriaville Ctr, Thunder Bay, ON, Canada
来源
PLOS ONE | 2024年 / 19卷 / 10期
关键词
HEALTH; COUNTRIES; EXPOSURE;
D O I
10.1371/journal.pone.0312117
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Background Homelessness represents a widespread social issue globally, yet the risk of neurodegenerative diseases (NDDs) associated with people experiencing homelessness (PEH) has not received sufficient attention. Therefore, this study aimed to explore the risk of NDDs among PEH and its variation across countries and regions through meta-analysis and systematic review.Methods Searching from databases such as PubMed and Web of Science, relevant research articles on PEH and NDDs were identified. After multiple screening, eight articles were selected for meta-analysis. Statistical methods and models were used to evaluate the association between PEH and NDDs, stratified by disease type and country.Results We found that PEH had a 51% higher risk of NDDs (OR = 1.51 (95% CI: 1.21, 1.89)) compared with those with stable housing. Specifically, PEH had a significantly higher risk of developing multiple sclerosis (OR = 4.64 (95% CI: 1.96, 10.98)). Alzheimer's disease and related dementias (ADRD) (OR = 1.93 (95% CI: 1.34, 2.77)), dementia (OR = 1.69 (95% CI: 1.26, 2.27)), and cognitive impairment (OR = 1.07 (95% CI: 0.98, 1.16)) were all at higher risk. Furthermore, country and regional differences were observed, with countries such as Iran (OR = 4.64 (95% CI: 1.96, 10.98)), the Netherlands (OR = 2.14 (95% CI: 1.23, 3.73)), the United States (OR = 1.66 (95% CI: 1.25, 2.22)), and Canada (OR = 1.06 (95% CI: 1.01, 1.10)) showing a higher risk of NDDs among the PEH.Conclusions The study emphasizes the significant NDD risks among PEH, providing novel perspectives on this issue and shedding light on national disparities influenced by variations in healthcare systems and social environments. This will be beneficial for academia and government to prioritize the health of PEH with NDDs, aiming to mitigate disease incidence and economic burdens while preserving social stability and upholding basic human rights.
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共 59 条
  • [51] Emergence of breath testing as a new non-invasive diagnostic modality for neurodegenerative diseases
    Subramaniam, N. Siva
    Bawden, C. S.
    Waldvogel, H.
    Faull, R. M. L.
    Howarth, G. S.
    Snell, R. G.
    [J]. BRAIN RESEARCH, 2018, 1691 : 75 - 86
  • [52] A systematic review and meta-analysis of the global prevalence and determinants of COVID-19 vaccine acceptance and uptake in people living with HIV
    Sulaiman, Sahabi Kabir
    Musa, Muhammad Sale
    Tsiga-Ahmed, Fatimah Isma'il
    Sulaiman, Abdulwahab Kabir
    Bako, Abdulaziz Tijjani
    [J]. NATURE HUMAN BEHAVIOUR, 2024, 8 (01) : 100 - 114
  • [53] Persistent Homelessness and Violent Victimization Among Older Adults in the HOPE HOME Study
    Tong, Michelle S.
    Kaplan, Lauren M.
    Guzman, David
    Ponath, Claudia
    Kushel, Margot B.
    [J]. JOURNAL OF INTERPERSONAL VIOLENCE, 2021, 36 (17-18) : 8519 - 8537
  • [54] A Comprehensive Assessment to Enable Recovery of the Homeless: The HOP-TR Study
    Van Everdingen, Coline
    Bob Peerenboom, Peter
    Van Der Velden, Koos
    Delespaul, Philippe A. E. G.
    [J]. FRONTIERS IN PUBLIC HEALTH, 2021, 9
  • [55] Self-reported care needs of Dutch homeless people with and without a suspected intellectual disability: a 1.5-year follow-up study
    Van Straaten, Barbara
    Rodenburg, Gerda
    Van der Laan, Jorien
    Boersma, Sandra N.
    Wolf, Judith R. L. M.
    Van de Mheen, Dike
    [J]. HEALTH & SOCIAL CARE IN THE COMMUNITY, 2017, 25 (01) : 123 - 136
  • [56] Infectious Diseases Among People Experiencing Homelessness: A Systematic Review of the Literature in the United States and Canada, 2003-2022
    Waddell, Caroline J.
    Saldana, Carlos S.
    Schoonveld, Megan M.
    Meehan, Ashley A.
    Lin, Christina K.
    Butler, Jay C.
    Mosites, Emily
    [J]. PUBLIC HEALTH REPORTS, 2024, 139 (05) : 532 - 548
  • [57] Ye Victor M, 2019, Dela J Public Health, V5, P74, DOI 10.32481/djph.2019.12.021
  • [58] A comparison of health and socioeconomic gradients in health between the United States and Canada
    Zajacova, Anna
    Siddiqi, Arjumand
    [J]. SOCIAL SCIENCE & MEDICINE, 2022, 306
  • [59] Cold Weather Conditions and Risk of Hypothermia Among People Experiencing Homelessness: Implications for Prevention Strategies
    Zhang, Paige
    Wiens, Kathryn
    Wang, Ri
    Luong, Linh
    Ansara, Donna
    Gower, Stephanie
    Bassil, Kate
    Hwang, Stephen W.
    [J]. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 2019, 16 (18)