A recent update on childhood obesity: aetiology, treatment and complications

被引:1
作者
Hawton, Katherine [1 ,2 ,3 ]
Shirodkar, Diksha [2 ,3 ]
Siese, Thomas [4 ]
Hamilton-Shield, Julian P. [2 ,5 ]
Giri, Dinesh [1 ,2 ,3 ]
机构
[1] Bristol Royal Hosp Children, Paediat & Endocrinol Dept, Upper Maudlin St, Bristol BS2 8BJ, England
[2] Univ Hosp Bristol & Weston NHS Fdn Trust, Bristol Royal Hosp Children, Bristol, England
[3] Univ Bristol, Bristol, England
[4] Univ Hosp Plymouth, Plymouth, England
[5] Univ Hosp Bristol & Weston NHS Fdn Trust, NIHR Biomed Res Ctr Nutr Theme, Bristol, England
关键词
obesity; overweight; excess weight; metabolic; dietary; type 2 diabetes mellitus; BODY-MASS INDEX; IDIOPATHIC INTRACRANIAL HYPERTENSION; INDIAN ACADEMY; BARIATRIC SURGERY; YOUNG-ADULTS; WEIGHT-LOSS; CHILDREN; MANAGEMENT; ADOLESCENTS; PREVALENCE;
D O I
10.1515/jpem-2024-0316
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Obesity is a complex, chronic condition characterised by excess adiposity. Rates of obesity in childhood and adolescence are increasing worldwide, with a corresponding increase in adulthood. The aetiology of obesity is multifactorial and results from a combination of endocrine, genetic, environmental and societal factors. Population level approaches to reduce the prevalence of childhood obesity worldwide are urgently needed. There are wide-ranging complications from excess weight affecting every system in the body, which lead to significant morbidity and reduced life expectancy. Treatment of obesity and its complications requires a multi-faceted, biopsychosocial approach incorporating dietary, exercise and psychological treatments. Pharmacological treatments for treating childhood obesity have recently become available, and there is further development of new anti-obesity medications in the pipeline. In addition, bariatric surgery is being increasingly recognised as a treatment option for obesity in adolescence providing the potential to reverse complications related to excess weight. In this review, we present an update on the prevalence, aetiology, complications and treatment of childhood obesity.
引用
收藏
页码:429 / 441
页数:13
相关论文
共 88 条
[41]   Interventions aimed at preventing and reducing overweight/obesity among children and adolescents: a meta-synthesis [J].
Kobes, A. ;
Kretschmer, T. ;
Timmerman, G. ;
Schreuder, P. .
OBESITY REVIEWS, 2018, 19 (08) :1065-1079
[42]   Genetic and Syndromic Causes of Obesity and its Management [J].
Koves, Ildiko H. ;
Roth, Christian .
INDIAN JOURNAL OF PEDIATRICS, 2018, 85 (06) :478-485
[43]  
Kyrou I., 2000, Endotext
[44]   GLP-1/GIP analogs: potential impact in the landscape of obesity pharmacotherapy [J].
Lafferty, Ryan. A. A. ;
Flatt, Peter. R. R. ;
Irwin, Nigel .
EXPERT OPINION ON PHARMACOTHERAPY, 2023, 24 (05) :587-597
[45]   Maternal smoking in pregnancy association with childhood adiposity and blood pressure [J].
Li, L. ;
Peters, H. ;
Gama, A. ;
Carvalhal, M. I. M. ;
Nogueira, H. G. M. ;
Rosado-Marques, V. ;
Padez, C. .
PEDIATRIC OBESITY, 2016, 11 (03) :202-209
[46]   Anxiety and depression in children and adolescents with obesity: a nationwide study in Sweden [J].
Lindberg, Louise ;
Hagman, Emilia ;
Danielsson, Pernilla ;
Marcus, Claude ;
Persson, Martina .
BMC MEDICINE, 2020, 18 (01)
[47]   Genetic studies of body mass index yield new insights for obesity biology [J].
Locke, Adam E. ;
Kahali, Bratati ;
Berndt, Sonja I. ;
Justice, Anne E. ;
Pers, Tune H. ;
Day, Felix R. ;
Powell, Corey ;
Vedantam, Sailaja ;
Buchkovich, Martin L. ;
Yang, Jian ;
Croteau-Chonka, Damien C. ;
Esko, Tonu ;
Fall, Tove ;
Ferreira, Teresa ;
Gustafsson, Stefan ;
Kutalik, Zoltan ;
Luan, Jian'an ;
Maegi, Reedik ;
Randall, Joshua C. ;
Winkler, Thomas W. ;
Wood, Andrew R. ;
Workalemahu, Tsegaselassie ;
Faul, Jessica D. ;
Smith, Jennifer A. ;
Zhao, Jing Hua ;
Zhao, Wei ;
Chen, Jin ;
Fehrmann, Rudolf ;
Hedman, Asa K. ;
Karjalainen, Juha ;
Schmidt, Ellen M. ;
Absher, Devin ;
Amin, Najaf ;
Anderson, Denise ;
Beekman, Marian ;
Bolton, Jennifer L. ;
Bragg-Gresham, L. ;
Buyske, Steven ;
Demirkan, Ayse ;
Deng, Guohong ;
Ehret, Georg B. ;
Feenstra, Bjarke ;
Feitosa, Mary F. ;
Fischer, Krista ;
Goel, Anuj ;
Gong, Jian ;
Jackson, Anne U. ;
Kanoni, Stavroula ;
Kleber, Marcus E. ;
Kristiansson, Kati .
NATURE, 2015, 518 (7538) :197-+
[48]   Bariatric surgery and long-term nutritional issues [J].
Lupoli, Roberta ;
Lembo, Erminia ;
Saldalamacchia, Gennaro ;
Avola, Claudia Kesia ;
Angrisani, Luigi ;
Capaldo, Brunella .
WORLD JOURNAL OF DIABETES, 2017, 8 (11) :464-474
[49]   Prevalence of overweight and obesity among children in the United Arab Emirates [J].
Malik, M. ;
Bakir, A. .
OBESITY REVIEWS, 2007, 8 (01) :15-20
[50]   Nutrition in the First 1000 Days: The Origin of Childhood Obesity [J].
Mameli, Chiara ;
Mazzantini, Sara ;
Zuccotti, Gian Vincenzo .
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 2016, 13 (09)