Cytotoxic compounds from Viscum coloratum (Kom.) Nakai

被引：0

作者：

Wen, Bo ^{[1
,2
]}

Pan, Juan ^{[1
,2
]}

Meng, Xin ^{[1
,2
]}

Hao, Zhi-Chao ^{[1
,2
]}

Guan, Wei ^{[1
,2
]}

Kuang, Hai-Xue ^{[1
,2
]}

Chen, Qing-Shan ^{[3
]}

Zhang, Li-li ^{[3
]}

Liu, Yan ^{[1
,2
]}

Yang, Bing-You ^{[1
,2
]}

机构：

[1] Heilongjiang Univ Chinese Med, Key Lab Basic & Applicat Res Beiyao, Minist Educ, Harbin, Peoples R China

[2] Tradit Chinese Med TCM Biol Genet Heilongjiang Pro, Harbin, Peoples R China

[3] Northeast Agr Univ, Coll Agr, Harbin 150030, Peoples R China

来源：

ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES | 2024年

基金：

中国国家自然科学基金;

关键词：

<italic>Viscum coloratum</italic> (Kom.) Nakai; diarylheptanoids; flavonoids; cytotoxicity; DIARYLHEPTANOIDS; SEEDS;

D O I：

10.1515/znc-2023-0170

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two new compounds (1-2) and a new artificial product (3) together with fifteen known compounds (4-18) were isolated from Viscum coloratum (Kom.) Nakai. Their structures were established by analysis of their spectroscopic data including MS, 1D and 2D NMR spectra, and comparison with existing literature. All the compounds were assessed for their cytotoxic activity against 4T1 and LN229 cells (with cisplatin as the positive control), and the anti-LN229 cytotoxicity of compounds 3, 4 and 5 were greater than that of 4T1 cells.

引用

页数：7