Most Publications Regarding Platelet-Rich Plasma Use in the Knee Are From Asia, Investigate Injection for Osteoarthritis, and Show Outcome Improvement: A Scoping Review

被引：0

作者：

Baird, Henry B. G. ^{[1
]}

Ashy, Cody C. ^{[2
]}

Kodali, Prudhvi ^{[1
]}

Myer, Gregory D. ^{[3
,4
,5
,6
,7
]}

Murray, Iain R. ^{[8
]}

Pullen, W. Michael ^{[2
]}

Slone, Harris S. ^{[2
]}

机构：

[1] Med Univ South Carolina, Coll Med, Clin Sci Bldg,Deans Suite 601,Jonathan Lucas St, Charleston, SC 29425 USA

[2] Med Univ South Carolina, Dept Orthoped Surg & Phys Med, Charleston, SC USA

[3] Emory Sports Performance & Res Ctr SPARC, Flowery Branch, GA USA

[4] Emory Sports Med Ctr, Atlanta, GA USA

[5] Emory Univ, Sch Med, Dept Orthopaed, Atlanta, GA USA

[6] Micheli Ctr Sports Injury Prevent, Waltham, MA USA

[7] Cardiff Metropolitan Univ, Youth Phys Dev Ctr, Cardiff, Wales

[8] Univ Edinburgh, Edinburgh, Scotland

来源：

ARTHROSCOPY-THE JOURNAL OF ARTHROSCOPIC AND RELATED SURGERY | 2025年 / 41卷 / 04期

基金：

美国国家卫生研究院;

关键词：

CLASSIFICATION; PATHOLOGIES; PAIN;

D O I：

10.1016/j.arthro.2024.03.030

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

Purpose: To evaluate and synthesize the available literature related to platelet-rich plasma (PRP) treatment of knee pathologies and to provide recommendations to inform future research in the field. Methods: PubMed, CINAHL, and Scopus databases were queried on October 6, 2023. All identified citations were collated and uploaded into Covidence for screening and data extraction. Studies were included if they were human studies published in English with adult cohorts that received PRP as a procedural injection or surgical augmentation for knee pathologies with patient-reported outcome measures (PROMs) and level of evidence Levels I-IV. Results: Our search yielded 2,615 studies, of which 155 studies from 2006 to 2023 met the inclusion criteria. Median follow-up was 9 months (+/- 11.2 months). Most studies (75.5%) characterized the leukocyte content of PRP, although most studies (86%) did not use a comprehensive classification scheme. In addition, most studies were from Asia (50%) and Europe (32%) and were from a single center (96%). In terms of treatment, 74% of studies examined PRP as a procedural injection, whereas 26% examined PRP as an augmentation. Most studies (68%) examined treatment of knee osteoarthritis. Many studies (83%) documented significant improvements in PROMs, including 93% of Level III/IV evidence studies and 72% of Level I/II evidence studies, although most studies (70%) failed to include minimal clinically important difference values. The visual analog scale was the most-used PROM (58% of studies), whereas the Short Form Health Survey 36-item was the least-used PROM (5% of studies). Conclusions: Most published investigations of knee PRP are performed in Asia, investigate procedural injection for osteoarthritis, and show significant outcome improvements. In addition, this review highlights the need for better classification of PRP formulations. Level of Evidence: Level IV, scoping review of Level I-IV studies.

引用

页码：1184 / 1194.e19

页数：30