High Mortality Rates Among Individuals Misdiagnosed With Tuberculosis: A Matched Retrospective Cohort Study of Individuals Diagnosed With Tuberculosis in Brazil

被引：0

作者：

Thompson, Ryan R. ^{[1
]}

Kim, Sun ^{[1
]}

Pelissari, Daniele Maria ^{[2
]}

Harada, Luiza Ohana ^{[2
]}

Silva Jr, Jose Nildo de Barros ^{[2
]}

Oliveira, Patricia Bartholomay ^{[2
]}

Castro, Marcia C. ^{[1
]}

Cohen, Ted ^{[3
]}

Menzies, Nicolas A. ^{[1
]}

机构：

[1] Harvard TH Chan Sch Publ Hlth, Dept Global Hlth & Populat, 677 Huntington Ave,Bldg 1,Room 1106A, Boston, MA 02115 USA

[2] Minist Hlth, Hlth & Environm Surveillance Secretariat, Brasilia, Brazil

[3] Yale Sch Publ Hlth, Dept Epidemiol Microbial Dis, New Haven, CT USA

来源：

JOURNAL OF INFECTIOUS DISEASES | 2024年

基金：

美国国家卫生研究院;

关键词：

tuberculosis; Brazil; misdiagnosis; survival analysis; electronic medical records;

D O I：

10.1093/infdis/jiae531

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We conducted a matched retrospective cohort study comparing mortality among individuals receiving a false- positive tuberculosis (TB) diagnosis (n = 3701) to individuals correctly diagnosed with TB (n = 8595) in Brazil from 2007 to 2016. Over an average 5.4-year follow-up period, we estimated a mortality rate ratio of 1.95 (95% confidence interval, 1.80-2.11) for individuals incorrectly diagnosed with TB compared to controls. The leading causes of death among the misdiagnosed were malignant neoplasms (40.9%) and respiratory system disorders (15.9%), conditions with symptoms similar to TB. Our findings highlight the need for improved follow-up care after identification of false-positive cases to increase survival for this high-risk population.

引用

页数：4

共 9 条

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