Organ preservation in rectal cancer: the GRECCAR12 randomized phase 3 trial (NCT02514278)

被引：0
|
作者：
Vendrely, Veronique [1 ]
Fernandez, Benjamin [2 ]
Giraud, Nicolas [1 ]
Rouanet, Philippe [3 ]
Tuech, Jean-Jacques [4 ]
Cotte, Eddy [5 ]
Lefevre, Jeremie [6 ]
Dubois, Anne [7 ]
Germain, Adeline [8 ]
Camerlo, Antoine [6 ]
Lelong, Bernard [9 ]
Valverde, Alain [10 ]
Lakkis, Zaher [11 ]
Rivoire, Michel [12 ]
Desfourneaux, Veronique [13 ]
Conroy, Thierry [14 ]
Asselineau, Julien [15 ]
Denost, Quentin [16 ]
Frison, Eric [15 ]
Rullier, Eric [2 ]
机构：
[1] CHU Bordeaux, Radiotherapy, Bordeaux, France
[2] CHU Bordeaux, Surg, Bordeaux, France
[3] Inst Canc Montpellier, Surg, Montpellier, France
[4] CHU Rouen, Surg, Rouen, France
[5] CHU Lyon, Surg, Lyon, France
[6] APHP, Surg, Paris, France
[7] CHU Clermont Ferrand, Surg, Lermont Ferrand, France
[8] CHU Nancy, Surg, Nancy, France
[9] IPC, Surg, Marseille, France
[10] La Croix St Simon, Surg, Paris, France
[11] CHU Besancon, Surg, Esancon, France
[12] Ctr Leon Berard, Surg, Lyon, France
[13] CHU Rennes, Surg, Rennes, France
[14] Inst Cancerol Loraine, Oncol, Nancy, France
[15] CHU Bordeaux, USMR, Bordeaux, France
[16] Bordeaux Colorectal Inst, Surg, Bordeaux, France
来源：
RADIOTHERAPY AND ONCOLOGY | 2024年 / 194卷
关键词：
Organ preservation; Rectal cancer; Radiotherapy;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
1929
引用
收藏
页码：S1533 / S1534
页数：2
相关论文
共 50 条
  • [1] Organ preservation, for rectal cancer: general overview of the latest data from phase III randomized trials
    Ben Dhia, Syrine
    Chauviere, Damien
    Mitrea, Diana
    Schiappa, Renaud
    Loscos, Tanguy Pace
    Chamorey, Emmanuel
    Baron, David
    ACTA ONCOLOGICA, 2025, 64 : 120 - 128
  • [2] Organ preservation with chemoradiotherapy plus local excision for rectal cancer: 5-year results of the GRECCAR 2 randomised trial
    Rullier, Eric
    Vendrely, Veronique
    Asselineau, Julien
    Rouanet, Philippe
    Tuech, Jean-Jacques
    Valverde, Alain
    de Chaisemartin, Cecile
    Rivoire, Michel
    Trilling, Bertrand
    Jafari, Mehrdad
    Portier, Guillaume
    Meunier, Bernard
    Sieleznieff, Igor
    Bertrand, Martin
    Marchal, Frederic
    Dubois, Anne
    Pocard, Marc
    Rullier, Anne
    Smith, Denis
    Frulio, Nora
    Frison, Eric
    Denost, Quentin
    LANCET GASTROENTEROLOGY & HEPATOLOGY, 2020, 5 (05): : 465 - 474
  • [3] To Drain or Not to Drain Infraperitoneal Anastomosis After Rectal Excision for Cancer The GRECCAR 5 Randomized Trial
    Denost, Quentin
    Rouanet, Philippe
    Faucheron, Jean-Luc
    Panis, Yves
    Meunier, Bernard
    Cotte, Eddy
    Meurette, Guillaume
    Kirzin, Sylvain
    Sabbagh, Charles
    Loriau, Jerome
    Benoist, Stephane
    Mariette, Christophe
    Sielezneff, Igor
    Lelong, Bernard
    Mauvais, Francois
    Romain, Benoit
    Barussaud, Marie-Line
    Germain, Christine
    Picat, Marie-Quitterie
    Rullier, Eric
    Laurent, Christophe
    ANNALS OF SURGERY, 2017, 265 (03) : 474 - 480
  • [4] Randomized Phase 3 Trial Comparing Preoperative and Postoperative Chemoradiotherapy With Capecitabine for Locally Advanced Rectal Cancer
    Park, Jin-hong
    Yoon, Sang Min
    Yu, Chang Sik
    Kim, Jong Hoon
    Kim, Tae Won
    Kim, Jin Cheon
    CANCER, 2011, 117 (16) : 3703 - 3712
  • [5] The safety and efficacy of total mesorectal excision (TME) surgery following dose-escalation: Surgical outcomes from the organ preservation in early rectal adenocarcinoma (OPERA) trial, a European multicentre phase 3 randomised trial (NCT02505750)
    Sun Myint, Arthur
    Rao, Christopher
    Barbet, Nicolas
    Thamphya, Brice
    Pace-Loscos, Tanguy
    Schiappa, Renaud
    Magne, Nicolas
    Martel-Lafay, Isabelle
    Mineur, Laurent
    Deberne, Melanie
    Zilli, Thomas
    Dhadda, Amandeep
    Gerard, Jean Pierre
    COLORECTAL DISEASE, 2023, 25 (11) : 2160 - 2169
  • [6] NORAD01-GRECCAR16 multicenter phase III non-inferiority randomized trial comparing preoperative modified FOLFIRINOX without irradiation to radiochemotherapy for resectable locally advanced rectal cancer (intergroup FRENCH-GRECCAR- PRODIGE trial)
    Brouquet, Antoine
    Bachet, Jean-Baptiste
    Huguet, Florence
    Karoui, Mehdi
    Artru, Pascal
    Sabbagh, Charles
    Lefevre, Jeremie H.
    Vernerey, Dewi
    Mariette, Christophe
    Vicaut, Eric
    Benoist, Stephane
    BMC CANCER, 2020, 20 (01)
  • [7] Intentional Watch and Wait or Organ Preservation Surgery Following Neoadjuvant Chemoradiotherapy Plus Consolidation CAPEOX for MRI-defined Low-risk Rectal Cancer Findings From a Prospective Phase 2 Trial (PKUCH-R01 Trial, NCT02860234)
    Wang, Lin
    Zhang, Xiao-Yan
    Zhao, Yi-Ming
    Li, Shi-Jie
    Li, Zhong-Wu
    Sun, Ying-Shi
    Wang, Wei-Hu
    Wu, Ai-Wen
    ANNALS OF SURGERY, 2023, 277 (04) : 647 - 654
  • [8] A multicentric randomized controlled trial on the impact of lengthening the interval between neoadjuvant radiochemotherapy and surgery on complete pathological response in rectal cancer (GRECCAR-6 trial): rationale and design
    Jérémie H Lefevre
    Alexandra Rousseau
    Magali Svrcek
    Yann Parc
    Tabassome Simon
    Emmanuel Tiret
    BMC Cancer, 13
  • [9] A phase III randomised trial on the addition of a contact X-ray brachytherapy boost to standard neoadjuvant chemo-radiotherapy for organ preservation in early rectal adenocarcinoma: 5 year results of the OPERA trial
    Baron, D.
    Loscos, T. Pace
    Schiappa, R.
    Barbet, N.
    Dost, E.
    Ben Dhia, S.
    Soltani, S.
    Mineur, L.
    Martel, I.
    Horn, S.
    Picardi, C.
    Stewart, A.
    Cotte, E.
    Coquard, R.
    Baudin, G.
    Evesque, L.
    Dhadda, A.
    Myint, A. Sun
    Gerard, J. P.
    Doyen, J.
    ANNALS OF ONCOLOGY, 2025, 36 (02) : 208 - 215
  • [10] A multicentric randomized controlled trial on the impact of lengthening the interval between neoadjuvant radiochemotherapy and surgery on complete pathological response in rectal cancer (GRECCAR-6 trial): rationale and design
    Lefevre, Jeremie H.
    Rousseau, Alexandra
    Svrcek, Magali
    Parc, Yann
    Simon, Tabassome
    Tiret, Emmanuel
    BMC CANCER, 2013, 13
12345