Prevention and Management of Posterior Wound Complications Following Oncologic Spine Surgery: Narrative Review of Available Evidence and Proposed Clinical Decision-Making Algorithm

被引:1
作者
Leary, Owen P. [1 ]
Setty, Aayush [1 ]
Gong, Jung Ho [1 ]
Ali, Rohaid [1 ]
Fridley, Jared S. [1 ]
Fisher, Charles G. [2 ]
Sahgal, Arjun [3 ]
Rhines, Laurence D. [4 ]
Reynolds, Jeremy J. [5 ]
Lazary, Aron [6 ]
Laufer, Ilya [7 ]
Gasbarrini, Alessandro [8 ]
Dea, Nicolas [2 ]
Verlaan, Jorrit-Jan [9 ]
Bettegowda, Chetan [10 ]
Boriani, Stefano [8 ]
Mesfin, Addisu [11 ]
Luzzati, Alessandro [12 ]
Shin, John H. [13 ]
Cecchinato, Riccardo [12 ]
Hornicek, Francis J. [14 ]
Goodwin, Matthew L. [15 ]
Gokaslan, Ziya L. [1 ]
机构
[1] Brown Univ, Rhode Isl Hosp, Warren Alpert Med Sch, Dept Neurosurg, APC-6, Providence, RI 02903 USA
[2] Univ British Columbia, Combined Neurosurg & Orthopaed Spine Program, Vancouver, BC, Canada
[3] Univ Toronto, Sunnybrook Hosp, Dept Radiat Oncol, Toronto, ON, Canada
[4] Univ Texas MD Anderson Canc Ctr, Dept Neurosurg, Houston, TX USA
[5] Oxford Univ Hosp, Oxford Spinal Surg Unit, Oxford, England
[6] Buda Hlth Ctr, Natl Ctr Spinal Disorders, Budapest, Hungary
[7] NYU, Grossman Sch Med, Dept Neurosurg, New York, NY USA
[8] Univ Bologna, Ist Ortoped Rizzoli, Bologna, Italy
[9] Univ Med Ctr Utrecht, Dept Orthoped, Utrecht, Netherlands
[10] Johns Hopkins Univ, Sch Med, Dept Neurosurg, Baltimore, MD USA
[11] Georgetown Univ, Medstar Orthopaed Inst, Sch Med, Dept Orthopaed Surg, Washington, DC USA
[12] Ambrogio Hosp, IRCCS Galeazzi, Milan, Italy
[13] Harvard Med Sch, Massachusetts Gen Hosp, Dept Neurosurg, Boston, MA USA
[14] Univ Miami, Miller Sch Med, Dept Orthopaed, Miami, FL USA
[15] Washington Univ, Sch Med St Louis, Dept Orthopaed Surg, St Louis, MO USA
关键词
surgical site infection; wound dehiscence; spinal oncology; clinical algorithm; spine surgery; SURGICAL-SITE-INFECTION; VANCOMYCIN POWDER; RISK-FACTORS; EN-BLOC; ANTIBIOTIC-THERAPY; FUSION; MORTALITY; OUTCOMES; DISEASE; QUALITY;
D O I
10.1177/21925682241237486
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Study DesignNarrative Review.ObjectiveContextualized by a narrative review of recent literature, we propose a wound complication prevention and management algorithm for spinal oncology patients. We highlight available strategies and motivate future research to identify optimal and individualized wound management for this population.MethodsWe conducted a search of recent studies (2010-2022) using relevant keywords to identify primary literature in support of current strategies for wound complication prevention and management following spine tumor surgery. When primary literature specific to spine tumor cases was not available, data were extrapolated from studies of other spine surgery populations. Results were compiled into a proposed clinical algorithm to guide practice considering available evidence.ResultsBased on available literature, we recommend individualized stratification of patients according to identifiable risk factors for wound complication and propose several interventions which might be employed preventatively, including intrawound antibiotic administration, negative pressure wound therapy, and primary flap closure of the surgical wound. Of these, the available evidence, weighing possible risks vs benefits, most strongly favors primary flap closure of surgical wounds, particularly for patients with multiple risk factors. A secondary algorithm to guide management of wound complications is also proposed.ConclusionsWound complications such as SSI and dehiscence remain a significant source of morbidity following spine tumor surgery. Triaging patients on an individualized basis according to risk factors for complication may aid in selecting appropriate prophylactic strategies to prevent these complications. Future research in this area is still needed to strengthen recommendations.
引用
收藏
页码:143S / 156S
页数:14
相关论文
共 121 条
[21]   Surgery for primary vertebral tumors: En bloc versus intralesional resection [J].
Chi, John H. ;
Sciubba, Daniel M. ;
Rhines, Laurence D. ;
Gokaslan, Ziya L. .
NEUROSURGERY CLINICS OF NORTH AMERICA, 2008, 19 (01) :111-+
[22]  
Choi Ho Seok, 2016, Korean J Spine, V13, P20, DOI 10.14245/kjs.2016.13.1.20
[23]   Optimizing Successful Outcomes in Complex Spine Reconstruction Using Local Muscle Flaps [J].
Cohen, Leslie E. ;
Fullerton, Natalia ;
Mundy, Lily R. ;
Weinstein, Andrew L. ;
Fu, Kai-Ming ;
Ketner, Jill J. ;
Haertl, Roger ;
Spector, Jason A. .
PLASTIC AND RECONSTRUCTIVE SURGERY, 2016, 137 (01) :295-301
[24]  
Cook BW, 2016, Spine J, V16, pS261, DOI DOI 10.1016/J.SPINEE.2016.07.351
[25]   Spinal infections in patients with compromised immune systems [J].
Cunningham, Matthew E. ;
Girardi, Federico ;
Papadopoulos, Elias C. ;
Cammisa, Frank P. .
CLINICAL ORTHOPAEDICS AND RELATED RESEARCH, 2006, (444) :73-82
[26]   Closure of Complex Posterior Midline Defects After Spinal Surgery With Sensate Midline-based Perforator Flaps and the Long-term Results [J].
de Weerd, Louis ;
Solberg, Tore K. ;
Weum, Sven .
SPINE, 2015, 40 (23) :E1233-E1238
[27]   Metastatic Spine Disease: Should Patients With Short Life Expectancy Be Denied Surgical Care? An International Retrospective Cohort Study [J].
Dea, Nicolas ;
Versteeg, Anne L. ;
Sahgal, Arjun ;
Verlaan, Jorrit-Jan ;
Charest-Morin, Raphaele ;
Rhines, Laurence D. ;
Sciubba, Daniel M. ;
Schuster, James M. ;
Weber, Michael H. ;
Lazary, Aron ;
Fehlings, Michael G. ;
Clarke, Michelle J. ;
Arnold, Paul M. ;
Boriani, Stefano ;
Bettegowda, Chetan ;
Laufer, Ilya ;
Gokaslan, Ziya L. ;
Fisher, Charles G. .
NEUROSURGERY, 2020, 87 (02) :303-311
[28]   Risk factors for deep surgical site infection following thoracolumbar spinal surgery [J].
Deng, Hansen ;
Chan, Andrew K. ;
Ammanuel, Simon G. ;
Chan, Alvin Y. ;
Oh, Taemin ;
Skrehot, Henry C. ;
Edwards, Caleb S. ;
Kondapavulur, Sravani ;
Nichols, Amy D. ;
Liu, Catherine ;
Yue, John K. ;
Dhall, Sanjay S. ;
Clark, Aaron J. ;
Chou, Dean ;
Ames, Christopher P. ;
Mummaneni, Praveen, V .
JOURNAL OF NEUROSURGERY-SPINE, 2020, 32 (02) :292-301
[29]   Trends, Major Medical Complications, and Charges Associated With Surgery for Lumbar Spinal Stenosis in Older Adults [J].
Deyo, Richard A. ;
Mirza, Sohail K. ;
Martin, Brook I. ;
Kreuter, William ;
Goodman, David C. ;
Jarvik, Jeffrey G. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2010, 303 (13) :1259-1265
[30]   Complications After Adult Spinal Deformity Surgeries: All Are Not Created Equal [J].
Dinizo, Michael ;
Dolgalev, Igor ;
Passias, Peter G. ;
Errico, Thomas J. ;
Raman, Tina .
INTERNATIONAL JOURNAL OF SPINE SURGERY, 2021, 15 (01) :137-143