Chemotherapy Sparks Tertiary Lymphoid Structures in Metastatic Ovarian Cancer

被引：0

作者：

Melgar, Jesus Bravo ^{[1
,2
]}

Laoui, Damya ^{[1
,2
]}

机构：

[1] VIB, Ctr Inflammat Res, Lab Dendrit Cell Biol & Canc Immunotherapy, Brussels, Belgium

[2] Vrije Univ Brussel, Brussels Ctr Immunol, Lab Cellular & Mol Immunol, Brussels, Belgium

来源：

CLINICAL CANCER RESEARCH | 2025年 / 31卷 / 01期

关键词：

D O I：

10.1158/1078-0432.CCR-24-2738

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Ovarian cancer remains resistant to immunotherapy in most patients, highlighting the need to make these tumors more immunogenic. A recent study unveils how chemotherapy is able to induce cancer cell stress in metastatic ovarian carcinomas, inducing the formation of tertiary lymphoid structures that create a "hotter" tumor microenvironment.

引用

页码：10 / 11

页数：2

共 6 条

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