Objective. To analyze gender-related differences in patient and care characteristics and in toxicology findings in suspected cases of drug-facilitated crime (DFC). Methods. Observational cross-sectional study of all patients in suspected DFC cases attended in the emergency department of Hospital Clinico San Carlos and of their blood or urine samples analyzed by the National institute of Toxicology and Forensics in Madrid between March 1, 2015, and March 1, 2023. We analyzed variables from patient records and the toxicology reports according to gender. Results. A total of 514 suspected DFC episodes were studied; 101 (19.6%) were proactive crimes, 61 (11.9%) opportunistic, and 352 (68.5%) mixed. The median (interquartile range) age was 25 years (21-34 years), and 370 (72%) were women. Eighty-three percent of the patients had amnesia, and 48% of the cases involved sexual assault or robbery. Toxicology identified substances in 78% of the patients (alcohol, 53%; street drugs, 37%; and/or psychopharmaceuticals or opioids, 23%). Independent variables associated with female gender in the multivariate analysis, according to adjusted odds ratio (aORs) were age less than 25 years (aOR, 2.73; 95% CI, 1.75-4.24; P <.001); physician-referred emergency (aOR, 1.77; 95% CI, 1.12-2.80; P =.03); robbery (aOR, 0.25; 95% CI, 0.15-0.41; P <.001); alcohol-positive test result (aOR, 1.91; 95% CI, 1.21-3.00; P =.01); and a drug-positive result (aOR, 0.43; 95% CI, 0.28-0.64; P <.001). Police and a forensic physician intervened in 13% of the cases, and in such cases the victim was more likely to be female (aOR, 3.97; 95% CI, 1.41-11.13; P <.001). Toxicology identified the presence of an unknown substance in 39%, and a woman was less likely to be involved in such cases (aOR, 0.43; 95% CI, 0.28-0.67; P <.001). Conclusions. The majority of victims of DFCs were female, and the crimes were mixed, involving involve alcohol, psychopharmaceuticals or street drugs. Female victims were more likely to be under the age of 25 years, be referred to the emergency service by a physician, be attended by a forensic physician for sexual assault, and have an alcoholpositive toxicology report. Women were also less likely to report a robbery or have a toxicology report identifying drugs or an unknown substance.
