Development and Validation of an Integrative Risk Score for Future Risk of Crohn's Disease in Healthy First-Degree Relatives: A Multicenter Cohort

被引：0
作者：
Lee, Sun-ho [1 ,2 ]
Turpin, Williams [1 ,2 ]
Espin-garcia, Osvaldo [3 ,4 ,5 ,6 ]
Xu, Wei [3 ,4 ]
Croitoru, Kenneth [1 ,2 ]
机构：
[1] Univ Toronto, Temerty Fac Med, Div Gastroenterol & Hepatol, Toronto, ON, Canada
[2] Mt Sinai Hosp, Zane Cohen Ctr Digest Dis, Toronto, ON, Canada
[3] Univ Toronto, Div Biostat, Dalla Lana Sch Publ Hlth, Toronto, ON, Canada
[4] Univ Hlth Network, Dept Biostat, Princess Margaret Canc Ctr, Toronto, ON, Canada
[5] Univ Toronto, Dept Stat Sci, Toronto, ON, Canada
[6] Univ Western Ontario, Dept Epidemiol & Biostat, London, ON, Canada
来源：
GASTROENTEROLOGY | 2025年 / 168卷 / 01期
关键词：
D O I：
10.1053/j.gastro.2024.08.021
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
引用
收藏
页数：8
相关论文
共 10 条
  • [1] PICRUSt2 for prediction of metagenome functions
    Douglas, Gavin M.
    Maffei, Vincent J.
    Zaneveld, Jesse R.
    Yurgel, Svetlana N.
    Brown, James R.
    Taylor, Christopher M.
    Huttenhower, Curtis
    Langille, Morgan G. I.
    [J]. NATURE BIOTECHNOLOGY, 2020, 38 (06) : 685 - 688
  • [2] RANDOM SURVIVAL FORESTS
    Ishwaran, Hemant
    Kogalur, Udaya B.
    Blackstone, Eugene H.
    Lauer, Michael S.
    [J]. ANNALS OF APPLIED STATISTICS, 2008, 2 (03) : 841 - 860
  • [3] Anti-Microbial Antibody Response is Associated With Future Onset of Crohn's Disease Independent of Biomarkers of Altered Gut Barrier Function, Subclinical Inflammation, and Genetic Risk
    Lee, Sun-Ho
    Turpin, Williams
    Espin-Garcia, Osvaldo
    Garay, Juan Antonio Raygoza
    Smith, Michelle I.
    Leibovitzh, Haim
    Goethel, Ashleigh
    Turner, Dan
    Mack, David
    Deslandres, Colette
    Cino, Maria
    Aumais, Guy
    Panaccione, Remo
    Jacobson, Kevan
    Bitton, Alain
    Steinhart, A. Hillary
    Huynh, Hien Q.
    Princen, Fred
    Moayyedi, Paul
    Griffiths, Anne M.
    Silverberg, Mark S.
    Paterson, Andrew D.
    Xu, Wei
    Croitoru, Kenneth
    [J]. GASTROENTEROLOGY, 2021, 161 (05) : 1540 - 1551
  • [4] Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease
    McGovern, Dermot P. B.
    Jones, Michelle R.
    Taylor, Kent D.
    Marciante, Kristin
    Yan, Xiaofei
    Dubinsky, Marla
    Ippoliti, Andy
    Vasiliauskas, Eric
    Berel, Dror
    Derkowski, Carrie
    Dutridge, Deb
    Fleshner, Phil
    Shih, David Q.
    Melmed, Gil
    Mengesha, Emebet
    King, Lily
    Pressman, Sheila
    Haritunians, Talin
    Guo, Xiuqing
    Targan, Stephan R.
    Rotter, Jerome I.
    [J]. HUMAN MOLECULAR GENETICS, 2010, 19 (17) : 3468 - 3476
  • [5] Expert opinion for use of faecal calprotectin in diagnosis and monitoring of inflammatory bowel disease in daily clinical practice
    Reenaers, Catherine
    Bossuyt, Peter
    Hindryckx, Pieter
    Vanpoucke, Hilde
    Cremer, Anneline
    Baert, Filip
    [J]. UNITED EUROPEAN GASTROENTEROLOGY JOURNAL, 2018, 6 (08) : 1117 - 1125
  • [6] SPRINZ H, 1961, AM J PATHOL, V39, P681
  • [7] Risk Factors Associated With Progression to Intestinal Complications of Crohn's Disease in a Population-Based Cohort
    Thia, Kelvin T.
    Sandborn, William J.
    Harmsen, William S.
    Zinsmeister, Alan R.
    Loftus, Edward V., Jr.
    [J]. GASTROENTEROLOGY, 2010, 139 (04) : 1147 - 1155
  • [8] Serum Biomarkers Identify Patients Who Will Develop Inflammatory Bowel Diseases Up to 5 Years Before Diagnosis
    Torres, Joana
    Petralia, Francesca
    Sato, Takahiro
    Wang, Pei
    Telesco, Shannon E.
    Choung, Rok Seon
    Strauss, Richard
    Li, Xiao-Jun
    Laird, Renee M.
    Gutierrez, Ramiro L.
    Porter, Chad K.
    Plevy, Scott
    Princen, Fred
    Murray, Joseph A.
    Riddle, Mark S.
    Colombel, Jean-Frederic
    [J]. GASTROENTEROLOGY, 2020, 159 (01) : 96 - 104
  • [9] Crohn's disease
    Torres, Joana
    Mehandru, Saurabh
    Colombel, Jean-Frederic
    Peyrin-Biroulet, Laurent
    [J]. LANCET, 2017, 389 (10080) : 1741 - 1755
  • [10] Increased Intestinal Permeability Is Associated With Later Development of Crohn 's Disease
    Turpin, Williams
    Lee, Sun-Ho
    Garay, Juan Antonio Raygoza
    Madsen, Karen L.
    Meddings, Jonathan B.
    Bedrani, Larbi
    Power, Namita
    Espin-Garcia, Osvaldo
    Xu, Wei
    Smith, Michelle, I
    Griffiths, Anne M.
    Moayyedi, Paul
    Turner, Dan
    Seidman, Ernest G.
    Steinhart, A. Hillary
    Marshall, John K.
    Jacobson, Kevan
    Mack, David
    Hien Huynh
    Bernstein, Charles N.
    Paterson, Andrew D.
    Croitoru, Kenneth
    [J]. GASTROENTEROLOGY, 2020, 159 (06) : 2092 - 2100.e5
1