Objectives: To explore nursing students' perceptions and understanding of artificial intelligence (AI), aiming to identify and address critical knowledge gaps to support effective integration into educational practices. Methods: An exploratory qualitative study was carried out using semi-structured interviews with 20 nursing students from King Saud University, Riyadh, Saudi Arabia, in October 2023. Data collection focused on their definitions, conceptualizations, and perspectives regarding AI in healthcare. Results: A total of 3 key themes emerged: I) transformation, where AI represents a shift in nursing education from traditional methods to technological integration; II) power, viewing AI as a driver of knowledge creation and scientific advancement; and III) use of technology, focusing on AI applications to enhance efficiency, automate tasks, and augment human abilities across sectors. Conclusion: The study highlights the need to integrate AI-related content into nursing curriculum, preparing students for its application in healthcare. These insights emphasize AI's role in shaping the future of nursing education and practice.