L-Tyrosine and L-DOPA: Promising scaffolds for the synthesis of biologically active compounds

被引：0

作者：

Ndayiragije, Euphrem ^{[1
,2
]}

Caumul, Prakashanand ^{[1
]}

Joondan, Nausheen ^{[1
]}

Bhowon, Minu Gupta ^{[1
]}

Laulloo, Sabina Jhaumeer ^{[1
]}

机构：

[1] Univ Mauritius, Fac Sci, Dept Chem, Reduit, Mauritius

[2] Univ Burundi, Fac Sci, Dept Chem, Bujumbura, Burundi

来源：

COMPTES RENDUS CHIMIE | 2024年 / 27卷

关键词：

L-Tyrosine; L-DOPA; Physicochemical properties; Biological activities; BOVINE SERUM-ALBUMIN; ACID-BASED SURFACTANTS; IN-VITRO; ANTIOXIDANT ACTIVITY; CHAIN-LENGTH; DESIGN; HYDROXYTYROSOL; ANTIBACTERIAL; DERIVATIVES; ESTERS;

D O I：

10.5802/crchim.342

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This review reports the synthetic strategies as well as the physicochemical and biological properties of L-tyrosine and 3,4-dihydroxyphenyl-L-alanine (L-DOPA) esters, amides, and imine derivatives including dopamines and tyrosol derivatives from 2010 to 2024. The variations in head group and hydrophilic chain were found to influence the physicochemical properties such as critical micelle concentration (CMC), lipophilicity, and surface tension. The biological properties of the previously reported L-tyrosine and L-DOPA derivatives such as radical scavenging, antibacterial, antiproliferative, and anti-Parkinson activities are also reported.

引用

页数：20

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