Developmental Toxicity of Micro(Nano)Plastics (MNPs) Exposure in Mammals: A Mini-Review

被引:1
作者
Xia, Gongxiang [1 ]
Wan, Teng [1 ]
Chen, Zhuan [1 ]
Liu, Cuiqing [1 ]
Li, Ran [1 ]
机构
[1] Zhejiang Chinese Med Univ, Zhejiang Int Sci & Technol Cooperat Base Air Pollu, Sch Publ Hlth, Hangzhou 310053, Peoples R China
基金
中国国家自然科学基金;
关键词
micro(nano)plastics; developmental toxicity; mammals; placental barrier; neurodevelopmental toxicity; MICROPLASTICS; NANOPLASTICS; MICE;
D O I
10.3390/toxics13030224
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Micro(nano)plastics (MNPs) pose a significant threat to both ecological environments and human health. This review systematically examines the developmental toxicity of MNPs in mammals, with a particular focus on the impact of maternal and paternal exposure on offspring. Evidence indicates that MNPs can cross placental barriers, inducing abnormal development of embryos, fetuses, and placentas. This disruption leads to a range of adverse outcomes, including neurodevelopmental abnormalities, behavioral disorders, reproductive system damage, etc., in offspring. Through a comprehensive analysis of the existing literature, this review aims to provide a foundation for future research on the developmental toxicity of MNPs and highlight the urgent need for action to mitigate the detrimental effects of MNPs on human health and ecosystem integrity.
引用
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页数:19
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