Acute Liver Injury and Kratom Use: A Case Report

This case report reviews a patient who presented to the hospital with drug-induced liver injury secondary to kratom use. Although drug-induced liver injury due to kratom ingestion is relatively rare, the incidence in the United States is climbing rapidly as the recreational use of kratom increases. The patient is a 42-year-old woman who presented with malaise, abdominal pain, and jaundice. The patient exercised regularly and started kratom supplements to decrease fatigue. After 6 months of kratom use, the patient discontinued supplementation. One week later, she presented to the emergency department with jaundice and acute liver injury. (c) 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.