Luminescent Ru(II) complexes based on functionalised 1,10-phenanthroline derivatised ligands towards bioconjugated probes

被引：0

作者：

Ibbott, Alexandra R. ^{[1
]}

Fosco, Paula Miquel ^{[1
]}

Alenazy, Deemah M. ^{[1
]}

Pope, Simon J. A. ^{[1
]}

机构：

[1] Cardiff Univ, Sch Chem, Main Bldg, Cardiff CF10 3AT, Cymru, Wales

来源：

INORGANICA CHIMICA ACTA | 2025年 / 579卷

基金：

英国工程与自然科学研究理事会;

关键词：

Phenanthroline; Ruthenium; Bioconjugation; Luminescence; TRANSITION-METAL-COMPLEXES; RUTHENIUM(II) POLYPYRIDYL COMPLEXES; RHENIUM(I) COMPLEXES; DNA; PHOTOSENSITIZERS; PHOTOCHEMISTRY; CONSTRUCTION; PHOTOPHYSICS; CARBAMATE; PEPTIDES;

D O I：

10.1016/j.ica.2025.122561

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A series of photoluminescent, heteroleptic [Ru(bipy)2(Ln)](PF6)2 (2,2 '-bipyridine = bipy; Ln = 1,10-phenanthroline derivative) analogues have been prepared. Within the series of complexes the structural variation is provided by the ancillary ligand, Ln, which is based upon a 5-substituted 1,10-phenanthroline species. The synthesis of the ligands was achieved in two steps from 5,6-epoxy-5,6-dihydro-1,10-phenanthroline allowing a range of different morpholine, piperazine and piperidine derivatives to be attached to the 1,10-phenanthroline core at the 5-position. Furthermore, the synthetic utility of the piperazine derivative (L1) was demonstrated by bioconjugating a cholesteryl moiety to the ligand (yielding L8). Following complexation, the isolated Ru(II) complexes show classical 3MLCT characteristics with phosphorescent emission at 605-610 nm.

引用

页数：10

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