Protective role of Hsian-tsao ethanol extract against body fat, serum lipid profiles, and hepatic lipid profiles in high-fat diet-fed rats

被引：0

作者：

Cho, Ching-Chang ^{[1
]}

Yen, Gow-Chin ^{[2
]}

Lee, Hsin-Yi ^{[1
]}

Tsai, Chun-Tse ^{[1
]}

Chang, Wei-Tang ^{[3
]}

Hsu, Chin-Lin ^{[1
,4
]}

机构：

[1] Chung Shan Med Univ, Dept Nutr, Taichung, Taiwan

[2] Natl Chung Hsing Univ, Dept Food Sci & Biotechnol, Taichung, Taiwan

[3] Chinese Culture Univ, Dept Nutr & Hlth Sci, Taipei, Taiwan

[4] Chung Shan Med Univ Hosp, Dept Nutr, Taichung, Taiwan

来源：

JOURNAL OF FOOD AND DRUG ANALYSIS | 2025年 / 33卷 / 01期

关键词：

Anti-Obesity; Ethanol extract of Hisan-tsao; High-fat diet; Mesona procumbens Hemsl; Oxidative stress; MESONA-PROCUMBENS HEMSL; OXIDATIVE STRESS; CHOLESTEROL-METABOLISM; INTESTINAL MICROBIOTA; BINDING PROTEIN; GENE-EXPRESSION; INDUCED OBESITY; PPAR-GAMMA; ACID; ENZYMES;

D O I：

10.38212/2224-6614.3527

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

This study investigated the preventive effects of a 40% ethanol extract of Hsian-tsao (40EEHT) on obesity in high-fat diet (HFD)-induced obese rats. Male Wistar rats were administered 0, 100, 200, or 500 mg/kg of 40EEHT, resulting in reduced body weight, total body fat, and hepatic tissue weight after 8 weeks. 40EEHT also decreased adipocyte size, improved lipid profiles, alleviated oxidative stress, and enhanced hepatic antioxidant enzyme activities. Additionally, it regulated fatty acid metabolism by reducing lipogenesis and increasing lipolysis and b-oxidation, suggesting its potential as an anti-obesity dietary supplement.

引用

页码：48 / 60

页数：15

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