Protective role of Hsian-tsao ethanol extract against body fat, serum lipid profiles, and hepatic lipid profiles in high-fat diet-fed rats

被引：0
|
作者：
Cho, Ching-Chang [1 ]
Yen, Gow-Chin [2 ]
Lee, Hsin-Yi [1 ]
Tsai, Chun-Tse [1 ]
Chang, Wei-Tang [3 ]
Hsu, Chin-Lin [1 ,4 ]
机构：
[1] Chung Shan Med Univ, Dept Nutr, Taichung, Taiwan
[2] Natl Chung Hsing Univ, Dept Food Sci & Biotechnol, Taichung, Taiwan
[3] Chinese Culture Univ, Dept Nutr & Hlth Sci, Taipei, Taiwan
[4] Chung Shan Med Univ Hosp, Dept Nutr, Taichung, Taiwan
来源：
JOURNAL OF FOOD AND DRUG ANALYSIS | 2025年 / 33卷 / 01期
关键词：
Anti-Obesity; Ethanol extract of Hisan-tsao; High-fat diet; Mesona procumbens Hemsl; Oxidative stress; MESONA-PROCUMBENS HEMSL; OXIDATIVE STRESS; CHOLESTEROL-METABOLISM; INTESTINAL MICROBIOTA; BINDING PROTEIN; GENE-EXPRESSION; INDUCED OBESITY; PPAR-GAMMA; ACID; ENZYMES;
D O I：
10.38212/2224-6614.3527
中图分类号：
TS2 [食品工业];
学科分类号：
0832 ;
摘要：
This study investigated the preventive effects of a 40% ethanol extract of Hsian-tsao (40EEHT) on obesity in high-fat diet (HFD)-induced obese rats. Male Wistar rats were administered 0, 100, 200, or 500 mg/kg of 40EEHT, resulting in reduced body weight, total body fat, and hepatic tissue weight after 8 weeks. 40EEHT also decreased adipocyte size, improved lipid profiles, alleviated oxidative stress, and enhanced hepatic antioxidant enzyme activities. Additionally, it regulated fatty acid metabolism by reducing lipogenesis and increasing lipolysis and b-oxidation, suggesting its potential as an anti-obesity dietary supplement.
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页数：15
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