Photocatalyst-Free Transformation of C(sp3)-H Bonds to Oxime Ethers via Photoinduced Hydrogen Atom Transfer

被引：0
|
作者：
Zhao, Yu-Lian [1 ,2 ]
Min, Xuehong [3 ]
Li, Lijing [1 ,2 ]
Han, Xiao-Le [1 ,2 ]
Wei, Yi [1 ,2 ]
Hu, Xiao-Qiang [1 ,2 ]
机构：
[1] South Cent Minzu Univ, Sch Chem & Mat Sci, Key Lab Catalysis & Energy Mat Chem, Minist Educ, Wuhan 430074, Peoples R China
[2] South Cent Minzu Univ, Sch Chem & Mat Sci, Hubei Key Lab Catalysis & Mat Sci, Wuhan 430074, Peoples R China
[3] Wuhan Business Univ, Hubei Prov Engn Res Ctr Racing Horse Detect & Appl, Equine Sci Res & Horse Doping Control Lab, Wuhan 430056, Peoples R China
来源：
ORGANIC LETTERS | 2024年 / 26卷 / 43期
基金：
中国国家自然科学基金;
关键词：
FUNCTIONAL-GROUP; SINGLET OXYGEN; ACTIVATION; AZIDE;
D O I：
10.1021/acs.orglett.4c03653
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Herein, a direct transformation of aliphatic C-H bonds to oxime ethers has been developed via light-promoted hydrogen atom transfer (HAT) in the absence of a photocatalyst. Singlet oxygen and chlorine radical are complementary C(sp(3))-H bond cleaving agents in this reaction, enabling the extraction of hydrogen atoms from a diverse range of compounds, like cycloalkanes, ethers, amines, amides, and cyclic sulfides. This method excels in transforming common aliphatic C-H bonds into valuable oxime ethers featuring abundant chemical feedstocks, good functional group tolerance, and catalyst free conditions.
引用
收藏
页码：9383 / 9388
页数：6
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