A Narrative Review of Moringa oleifera Lam., Moringaceae, Swietenia mahagoni L. Jacq., Meliaceae, and Momordica charantia L., Cucurbitaceae Plants Found in The Bahamas as Antidiabetes Phytomedicine

被引:0
作者
Miller, Gloria [1 ]
Grundmann, Oliver [1 ]
机构
[1] Univ Florida, Coll Pharm, Dept Med Chem, 1345 Ctr Dr,Room P3 12, Gainesville, FL 32611 USA
关键词
cerasee; diabetes; mahogany; moringa; traditional medicine; MECHANISMS; EXTRACTS;
D O I
10.1089/jmf.2024.0100
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Moringa (Moringa oleifera Lam., Moringaceae), West Indian mahogany (Swietenia mahagoni [L.] Jacq., Meliaceae), and Cerasee (Momordica charantia L., Cucurbitaceae) are plants that are used for medicinal purposes in The Bahamas. They have various medicinal uses, including treating diabetes, anemia, inflammation, dermatological issues, backaches, cold, flu, and gastrointestinal problems. This review aims to summarize the current knowledge about natural products found in The Bahamas that can be used to treat diabetes mellitus. The search terms "Moringa oleifera Lam.," "Swietenia mahagoni (L.)," "Momordica charantia L.," "Tecoma stans," "Persea americana," "Psidium guajava," "Hamelia patens," and "Carica papaya L." in combination with "diabetes" were utilized to obtain pertinent data by searching PubMed and Google Scholar. Moringa oleifera Lam. significantly decreased fasting glucose levels in rodents after 3 months of consumption. The ethanolic extract of S. mahagoni seeds and the methanol extract of its bark can decrease blood glucose levels. Momordica charantia L. and H. patens Jacq. produce the same hypoglycemic effects as metformin. The plant extracts and compounds of T. stans (L.) Juss. ex Kunth, P. americana Mill., P. guajava L., and C. papaya L. showed diverse pharmacological activities such as reducing fasting glucose, lowering blood pressure and blood sugar, decreasing total triglycerides and total cholesterol, and improving structural damage of cardiac muscles caused by diabetes. Literature analysis reveals that the diverse pharmacological activities of various plants native to The Bahamas show promise as a medicinal food in the treatment of diabetes.
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页码:119 / 126
页数:8
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共 46 条
  • [1] Phytogenic compounds from avocado (Persea americana L.) extracts; antioxidant activity, amylase inhibitory activity, therapeutic potential of type 2 diabetes
    Abd Elkader, Akwam M.
    Labib, Salah
    Taha, Taha F.
    Althobaiti, Fayez
    Aldhahrani, Adil
    Salem, Heba M.
    Saad, Ahmed
    Ibrahim, Faten M.
    [J]. SAUDI JOURNAL OF BIOLOGICAL SCIENCES, 2022, 29 (03) : 1428 - 1433
  • [2] A series of cinnamic acid derivatives and their inhibitory activity on intestinal α-glucosidase
    Adisakwattana, Sirichai
    Chantarasinlapin, Praew
    Thammarat, Haruthai
    Yibchok-Anun, Sirintorn
    [J]. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2009, 24 (05) : 1194 - 1200
  • [3] Antidiabetic activities of Tecoma stans (L.) Juss. ex Kunth
    Aguilar-Santamaria, L.
    Ramirez, G.
    Nicasio, P.
    Alegria-Reyes, C.
    Herrera-Arellano, A.
    [J]. JOURNAL OF ETHNOPHARMACOLOGY, 2009, 124 (02) : 284 - 288
  • [4] Ameliorative effects of Carica papaya extracts against type II diabetes-induced myocardial pathology and dysfunction in albino rats.
    Amin, Ali H.
    [J]. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2021, 28 (41) : 58232 - 58240
  • [5] Anthanont Pimjai, 2016, Journal of the Medical Association of Thailand, V99, P308
  • [6] Bailey C J, 1985, Diabetes Res, V2, P81
  • [7] Structure determination, bitterness evaluation and hepatic gluconeogenesis inhibitory activity of triterpenoids from the Momordica charantia fruit
    Deng, Yuanyuan
    Ma, Yongxuan
    Liu, Huijuan
    Zhang, Yan
    Wei, Zhencheng
    Liu, Guang
    Tang, Xiaojun
    Jia, Xuchao
    [J]. FOOD CHEMISTRY, 2022, 372
  • [8] Biological, nutritional, and therapeutic significance of Moringa oleifera Lam
    Dhakad, Ashok K.
    Ikram, Mohsin
    Sharma, Shivani
    Khan, Salman
    Pandey, Vijay V.
    Singh, Avtar
    [J]. PHYTOTHERAPY RESEARCH, 2019, 33 (11) : 2870 - 2903
  • [9] MECHANISMS OF DIABETIC COMPLICATIONS
    Forbes, Josephine M.
    Cooper, Mark E.
    [J]. PHYSIOLOGICAL REVIEWS, 2013, 93 (01) : 137 - 188
  • [10] Hypoglycemic effect of bitter melon compared with metformin in newly diagnosed type 2 diabetes patients
    Fuangchan, Anjana
    Sonthisombat, Paveena
    Seubnukarn, Tippawadee
    Chanouan, Rapeepan
    Chotchaisuwat, Pontap
    Sirigulsatien, Viruch
    Ingkaninan, Kornkanok
    Plianbangchang, Pinyupa
    Haines, Stuart T.
    [J]. JOURNAL OF ETHNOPHARMACOLOGY, 2011, 134 (02) : 422 - 428