The Effects of Carbonate on Candida albicans Filamentation, Biofilm Formation, and Antifungal Resistance

被引：0

作者：

Miedema, Trenton P. ^{[1
]}

Grooters, Kayla E. ^{[1
,2
]}

Cleary, Ian A. ^{[1
]}

机构：

[1] Grand Valley State Univ, Dept Biomed Sci, Allendale, MI 49401 USA

[2] Western Michigan Univ, Homer Stryker MD Sch Med, Dept Med, Kalamazoo, MI USA

来源：

MICROBIOLOGYOPEN | 2024年 / 13卷 / 06期

关键词：

antifungals; Candida albicans; carbonate; filamentation; SODIUM-BICARBONATE; SUSCEPTIBILITY; GROWTH;

D O I：

10.1002/mbo3.70008

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Candida albicans, a member of the normal microbial population of healthy humans, is an opportunistic pathogen that can cause serious disease in immunocompromised patients. An important virulence factor of C. albicans is the formation of biofilms. These organized communities of cells are efficient at attaching to host cells and implanted medical devices. Carbonate has been studied as an agricultural antifungal agent, and here we demonstrate that carbonate can affect filamentation, biofilm formation, and antifungal drug resistance in C. albicans.

引用

页数：7

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