FOXO1 promotes cancer cell growth through MDM2-mediated p53 degradation

被引：0

作者：

Tomiyasu, Haruki ^{[1
]}

Habara, Makoto ^{[1
]}

Hanaki, Shunsuke ^{[1
]}

Sato, Yuki ^{[1
]}

Miki, Yousei ^{[1
]}

Shimada, Midori ^{[2
]}

机构：

[1] Yamaguchi Univ, Fac Vet Sci, Dept Vet Biochem, Yamaguchi, Japan

[2] Nagoya Univ, Mol Biol, Grad Sch Med, Nagoya, Aichi, Japan

来源：

CANCER SCIENCE | 2025年 / 116卷

关键词：

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

P-1024

引用

页码：232 / 232

页数：1

共 50 条

[31] ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation [J].

Jer-Yen Yang ;

Cong S. Zong ;

Weiya Xia ;

Hirohito Yamaguchi ;

Qingqing Ding ;

Xiaoming Xie ;

Jing-Yu Lang ;

Chien-Chen Lai ;

Chun-Ju Chang ;

Wei-Chien Huang ;

Hsin Huang ;

Hsu-Ping Kuo ;

Dung-Fang Lee ;

Long-Yuan Li ;

Huang-Chun Lien ;

Xiaoyun Cheng ;

King-Jen Chang ;

Chwan-Deng Hsiao ;

Fuu-Jen Tsai ;

Chang-Hai Tsai ;

Aysegul A. Sahin ;

William J. Muller ;

Gordon B. Mills ;

Dihua Yu ;

Gabriel N. Hortobagyi ;

Mien-Chie Hung .

Nature Cell Biology, 2008, 10 :138-148

[32] MYL6B, a myosin light chain, promotes MDM2-mediated p53 degradation and drives HCC development [J].

Xingwang Xie ;

Xueyan Wang ;

Weijia Liao ;

Ran Fei ;

Nan Wu ;

Xu Cong ;

Qian Chen ;

Lai Wei ;

Yu Wang ;

Hongsong Chen .

Journal of Experimental & Clinical Cancer Research, 37

[33] Inhibition of MDM2-mediated p53 ubiquitination and degradation by ribosomal protein L5 [J].

Dai, MS ;

Lu, H .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (43) :44475-44482

[34] PRC1 promotes ovarian cancer progression by binding to RPL4 and increasing MDM2-mediated p53 ubiquitination [J].

Xu, Yinyin ;

Xu, Jiaxing ;

Xu, Kai ;

Zhang, Cancan ;

Wang, Fengmian ;

Zhang, Rong ;

Zhu, Pengfeng .

EXPERIMENTAL CELL RESEARCH, 2025, 447 (02)

[35] MYL6B, a myosin light chain, promotes MDM2-mediated p53 degradation and drives HCC development [J].

Xie, Xingwang ;

Wang, Xueyan ;

Liao, Weijia ;

Fei, Ran ;

Wu, Nan ;

Cong, Xu ;

Chen, Qian ;

Wei, Lai ;

Wang, Yu ;

Chen, Hongsong .

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2018, 37

[36] P53 stability and activity is regulated by Mdm2-mediated induction of alternative p53 translation products [J].

Yin, YL ;

Luciani, MG ;

Fåhraeus, R .

NATURE CELL BIOLOGY, 2002, 4 (06) :462-467

[37] Mdm2 promotes the rapid degradation of p53 [J].

Ygal Haupt ;

Ruth Maya ;

Anat Kazaz ;

Moshe Oren .

Nature, 1997, 387 :296-299

[38] p53 stability and activity is regulated by Mdm2-mediated induction of alternative p53 translation products [J].

Yili Yin ;

Charles W. Stephen ;

M. Gloria Luciani ;

Robin Fåhraeus .

Nature Cell Biology, 2002, 4 :462-467

[39] Mdm2 promotes the rapid degradation of p53 [J].

Haupt, Y ;

Maya, R ;

Kazaz, A ;

Oren, M .

NATURE, 1997, 387 (6630) :296-299

[40] A modified p53 overcomes mdm2-mediated oncogenic transformation: A potential cancer therapeutic agent [J].

Lin, JY ;

Jin, XH ;

Page, C ;

Sondak, VK ;

Jiang, GH ;

Reynolds, RK .

CANCER RESEARCH, 2000, 60 (20) :5895-5901

← 1 2 3 4 5 →