Association of Diabetic Ketoacidosis in Childhood New-Onset Type 1 Diabetes With Day of Presentation in Germany

被引：3

作者：

Kamrath, Clemens ^{[1
]}

Sindichakis, Marina ^{[2
]}

Auzanneau, Marie ^{[3
,4
]}

Schmid, Silke ^{[5
]}

Segerer, Hugo ^{[6
]}

Lahn, Valentina ^{[7
]}

Golembowsky, Sven ^{[8
]}

Roessner-Cold, Dorothee ^{[9
]}

Rauh, Kristina ^{[10
]}

Manuwald, Ulf ^{[11
]}

Holl, Reinhard W. ^{[3
,4
]}

机构：

[1] Justus Liebig Univ, Ctr Child & Adolescent Med, Giessen, Germany

[2] Klinikum Traunstein, Hosp Children & Adolescents, Traunstein, Germany

[3] Univ Ulm, Inst Epidemiol & Med Biometry, Comp Assisted Qual Assurance Med, Ulm, Germany

[4] German Ctr Diabet Res, Munich, Germany

[5] Dritter Orden Clin, Munich, Germany

[6] Univ Regensburg, Childrens Hosp St Hedwig, Regensburg, Germany

[7] Childrens Hosp Hamburg Altona, Hamburg, Germany

[8] Childrens Hosp Sana Clin Berlin Lichtenberg, Berlin, Germany

[9] Gilead Child Ctr Bielefeld, Bielefeld, Germany

[10] Childrens Hosp Chemnitz, Chemnitz, Germany

[11] Univ Appl Sci, Fac Appl Social Sci, Dresden, Germany

来源：

DIABETES CARE | 2024年 / 47卷 / 04期

关键词：

DIAGNOSIS; CHILDREN;

D O I：

10.2337/dc23-1643

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

OBJECTIVE Whether the day of the week on which the child presents affects timely diagnosis and risk of diabetic ketoacidosis (DKA) in children with new-onset type 1 diabetes (T1D) is not known. RESEARCH DESIGN AND METHODS We used data of 30,717 children with new-onset T1D during the last 10 years from the German Prospective Diabetes Registry. We determined the odds ratios of T1D diagnosis and DKA on a weekday, public holiday, and school vacation. RESULTS Compared with workdays, the odds ratios of being diagnosed with T1D were lower on weekends (0.39 [95% CI, 0.38-0.41]), public holidays (0.57 [0.53-0.63]), and school vacations (0.83 [0.80-0.85]). The odds of DKA diagnosis were also reduced on weekends (0.55 [0.52-0.59]), public holidays (0.73 [0.63-0.84]), and school vacations (0.85 [0.80-0.90]). Results did not change during the coronavirus 2019 pandemic. CONCLUSIONS New-onset T1D and DKA in children are more often diagnosed during weekdays than weekends and holidays.

引用

页码：649 / 652

页数：4

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