The Unique Challenge of Coronary Artery Disease in Adult Patients with Congenital Heart Disease

被引:0
作者
Borrelli, Nunzia [1 ]
Merola, Assunta [1 ]
Barracano, Rosaria [1 ]
Palma, Michela [1 ]
Altobelli, Ippolita [1 ]
Abbate, Massimiliana [1 ]
Papaccioli, Giovanni [1 ]
Ciriello, Giovanni Domenico [1 ]
Liguori, Carmen [1 ]
Sorice, Davide [1 ]
De Luca, Lorenzo [1 ]
Scognamiglio, Giancarlo [1 ]
Sarubbi, Berardo [1 ]
机构
[1] Monaldi Hosp, Adult Congenital Heart Dis & Familiar Arrhythmias, I-80131 Naples, Italy
关键词
congenital heart disease; coronary artery disease; atherosclerosis; cardiovascular risk factors; SWITCH OPERATION; GREAT-ARTERIES; ATHEROSCLEROTIC INVOLVEMENT; MYOCARDIAL-INFARCTION; AORTIC COARCTATION; GLUCOSE-METABOLISM; TURNER-SYNDROME; YOUNG-PATIENTS; ANOMALIES; TRANSPOSITION;
D O I
10.3390/jcm13226839
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Advances in medical and surgical interventions have resulted in a steady increase in the number of patients with congenital heart disease (CHD) reaching adult age. Unfortunately, this ever-growing population faces an added challenge: an increased risk of acquiring coronary artery disease. This review provides insight into the complex interactions between coronary artery disease and CHD in adults. We describe the peculiar features of cardiac anatomy in these patients, the possible role cardiac sequelae may play in an increased risk of myocardial ischemia, and the diagnostic challenges in this patient group. Furthermore, this review outlines the risk factors and potential mechanisms of accelerated atherosclerosis in adults with CHD by pointing out areas where current knowledge is incomplete and highlighting areas for further research. The review concludes by examining potential management strategies for this particular population, emphasizing the necessity for a multidisciplinary approach. Understanding the unique coronary risks that adults with CHD experience can enhance patient care and improve long-term results.
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页数:14
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