Vernal keratoconjunctivitis in human immunodeficiency positives: A case series

被引：0

作者：

Agarwal, Shweta ^{[1
]}

Srinivasan, Bhaskar ^{[1
]}

Iyer, Geetha ^{[1
]}

Patel, Nilay ^{[1
]}

Rajagopal, Rama ^{[1
]}

Gurumurthy, Srividya ^{[2
]}

Sudharshan, Sridharan ^{[3
]}

机构：

[1] Sankara Nethralaya, Med Res Fdn, CJ Shah Cornea Serv, Dr G Sitalakshmi Mem Clin Ocular Surface Disorders, 18 Coll Rd, Chennai 600006, Tamil Nadu, India

[2] Sankara Nethralaya, Med Res Fdn, SN SANMAR Ctr Excellence SJS, Chennai, Tamil Nadu, India

[3] Sankara Nethralaya, Med Res Fdn, Dept Uvea, Chennai, Tamil Nadu, India

来源：

INDIAN JOURNAL OF OPHTHALMOLOGY | 2025年 / 73卷 / 04期

关键词：

Allergic conjunctivitis; CD4; count; HIV; vernal keratoconjunctivitis; VIRUS; DISEASE; CHILDREN; IGE;

D O I：

10.4103/IJO.IJO_2314_24

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Purpose:To analyze the clinical profile of vernal keratoconjunctivitis (VKC) and its response to treatment in human immunodeficiency virus (HIV) patients and its relation with CD4 counts. Methods:This study is a retrospective observational case series of patients with HIV and VKC. Results:Thirteen patients presented with HIV and VKC, with 69.2% having a severe-grade VKC. Median age of onset of VKC was 5 years in children and 31.5 years in adults. Seventy percent had a drop in CD4 counts at the onset of VKC. The duration between diagnosis of HIV and onset of VKC was statistically less in adults than in children. Eleven were on highly active antiretroviral therapy at presentation, and three patients were changed to second line of therapy, two of whom showed worsening of VKC just before shifting. Conclusion:The study thus highlights the correlation between worsening of VKC and decrease in CD4 counts, and thus there is a need for aggressive management of HIV to prevent VKC-related complications.

引用

页码：599 / 602

页数：4

共 15 条

[1] Vernal keratoconjunctivitis in human immunodeficiency virus - The possible role of T-helper 1-T-helper 2 shift [J].