Image quality evaluation of imaging skins, a novel stretchable X-ray detector for intraoperative tumour imaging

被引:0
作者
Solène Dietsch [1 ]
Harry Allan [2 ]
Lukas Lindenroth [3 ]
Robert Moss [4 ]
Agostino Stilli [2 ]
Danail Stoyanov [1 ]
机构
[1] Wellcome/EPSRC Centre for Interventional and Surgical Sciences, University College London, London
[2] Department of Medical Physics and Biomedical Engineering, University College London, London
[3] X-ray Microscopy and Tomography Lab, The Francis Crick Institute, London
[4] School of Biomedical Engineering & Imaging Sciences, King’s College London, London
基金
英国工程与自然科学研究理事会;
关键词
Image quality; Scintillator; Soft materials; Stretchable sensor; X-ray detector;
D O I
10.1038/s41598-025-96768-z
中图分类号
学科分类号
摘要
This paper presents the development of a novel X-ray detector composed of silicone elastomer and GOS:Tb, which we refer to as imaging skins. These detectors were integrated into a custom X-ray system to convert radiation into visible light. Our study focused on how fabrication parameters such as thickness and concentration impact sensor linearity, considering their potential application directly on the skin or organs to identify tumour margins during surgery. In addition, we examined how the stretching capabilities of these detectors influenced the image quality. Our imaging detection stack demonstrated consistent linearity across various fabrication parameters with the coefficient of determination () more than 0.99998, showing that the silicone elastomer does not affect the conversion of the X-ray into light. We achieved a spatial resolution of 1.16–1.42 lp/mm at 10% of the Spatial Frequency Response using a 0.5-mm thick sensor. This study represents a first step towards integrating stretchable X-ray detectors into clinical settings, particularly on curved surfaces, to unlock their full potential in complex surgical configurations. It also highlights the need for a deeper understanding of the interactions between X-rays and detector materials to fully interpret the observed effects. © The Author(s) 2025.
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