Technical feasibility of delivering a simultaneous integrated boost in partial breast irradiation

被引:0
作者
Burton, Alex [1 ,2 ,3 ,4 ]
Cassar, Tamika [2 ]
Glenn, Christy [2 ]
Byrne, Keelan [2 ]
机构
[1] Peter MacCallum Canc Ctr, Dept Phys Sci, Melbourne, Vic 3000, Australia
[2] Univ Melbourne, Sir Peter MacCallum Dept Oncol, Parkville, Vic 3000, Australia
[3] RMIT Univ, Sch Sci, Melbourne, Vic 3000, Australia
[4] Australian Radiat Protect & Nucl Safety Agcy, Australian Clin Dosimetry Serv, Yallambie, Vic 3069, Australia
来源
PHYSICS & IMAGING IN RADIATION ONCOLOGY | 2024年 / 32卷
关键词
Partial breast irradiation; VMAT; Planning study; FRACTIONATION SCHEDULES; OPEN-LABEL; RADIOTHERAPY; MULTICENTER; CANCER; PHASE-3; TRIAL; RISK; HOLD;
D O I
10.1016/j.phro.2024.100659
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Feasibility of volumetric modulated arc therapy (VMAT) for partial breast irradiation (PBI) with simultaneous integrated boost (SIB) to tumour bed was investigated. Four plans were created for 10 patients: 30 Gy/5 fractions, 26 Gy/5 fractions with 30 Gy SIB, 40.05 Gy/15 fractions, and 40.05 Gy/15 fractions with 48 Gy SIB. SIB in the 5 fraction arm had reduced ipsilateral breast dose relative to uniform dose. SIB in the 15 fraction arm had noninferior conformity compared to uniform dose. Addition of SIB did not increase other organ-at-risk doses or plan complexity. VMAT PBI with SIB was feasible for both fractionation regimens.
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页数:4
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