Molecular biology: In competition, actin filament turnover saves the day

被引:0
|
作者
Suarez, Cristian [1 ]
Kovar, David R. [1 ,2 ]
机构
[1] Univ Chicago, Dept Mol Genet & Cell Biol, Chicago, IL 60637 USA
[2] Univ Chicago, Dept Biochem & Mol Biol, Chicago, IL 60637 USA
关键词
ARP2/3; COMPLEX; SIZE;
D O I
10.1016/j.cub.2024.12.036
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Cellular actin cytoskeleton networks compete for limited actin monomers. New in vitro reconstitutions with purified proteins reveal that without network turnover, the strongest networks monopolize all the resources. However, with turnover, weaker networks survive and coexist with stronger networks.
引用
收藏
页码:R101 / R104
页数:4
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