Hepatic iron overload

被引：0
作者：
Turlin, Bruno [1 ]
Allaume, Pierre [1 ]
机构：
[1] CHU Rennes, Hop Pontchaillou, Anat pathol, F-35003 Rennes, France
来源：
ANNALES DE PATHOLOGIE | 2024年 / 44卷 / 06期
关键词：
Iron overload; Perls staining; Hemochromatosis; GENETIC HEMOCHROMATOSIS; LIVER PATHOLOGY; SIDEROSIS; DISORDER;
D O I：
10.1016/j.annpat.2024.09.007
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
Iron is essential for functioning of cells and of the body as a whole. Perls staining allows the histopathological identification of iron deposits. By classifying hepatic siderosis as parenchymal, mesenchymal or mixed, it may guide the search for its etiology. HFE1 hemochromatosis is the most common siderosis. Its diagnosis is currently based on genetic analysis. Its expressivity being variable and its penetrance incomplete, the demonstration of hepatic siderosis may represent a mode of discovery. (c) 2024 Published by Elsevier Masson SAS.
引用
收藏
页码：461 / 469
页数：9
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