Two Cases of Intraocular Undifferentiated Pleomorphic Sarcoma

被引：0

作者：

Khatab, Sodaba ^{[1
]}

Colijn, Johanna Maria ^{[2
]}

Naus, Nicole ^{[2
]}

Verdijk, Robert M. ^{[1
,3
,4
]}

Hotte, Gijsbert ^{[1
]}

机构：

[1] Rotterdam Eye Hosp, Dept Oculoplast Orbital & Lacrimal Surg, Rotterdam, Netherlands

[2] Erasmus MC, Univ Med Ctr Rotterdam, Dept Ophthalmol, Rotterdam, Netherlands

[3] Erasmus MC, Univ Med Ctr Rotterdam, Dept Pathol, Sect Ophthalm Pathol, Rotterdam, Netherlands

[4] Leiden Univ, Med Ctr, Dept Pathol, Leiden, Netherlands

来源：

OCULAR ONCOLOGY AND PATHOLOGY | 2024年 / 10卷 / 04期

关键词：

Adult ocular oncology; Adult ocular tumours; Intraocular tumours; Ocular oncology; Orbital tumour; Sarcoma; SOFT-TISSUE SARCOMAS; TUMORS; SITE; PROSTHESIS; SPECTRUM; OUTCOMES; IMPLANT;

D O I：

10.1159/000541063

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Introduction: Undifferentiated pleomorphic sarcoma (UPS), formerly known as malignant fibrous histiocytoma, is a high-grade soft tissue sarcoma arising from mesenchymal stem cells. UPSs are rare and account for about 5% of all soft tissue sarcoma. UPSs arising in the head and neck are especially rare, comprising 1-3% of all UPSs. Case Presentation: In this report, we describe 2 cases of intraocular UPS. Both cases concern 68-year-old males: one developing a UPS in an eviscerated socket after a chronic fibrinous inflammation and the other years after ocular trauma. Conclusion: Our cases may support the hypothesis of chronic inflammation playing a role in sarcoma formation as they are characterized by a longstanding history of (surgical) trauma with signs of chronic inflammation and phthisis bulbi.

引用

页码：227 / 233

页数：7

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