I-Spin live, an open-source software based on blind-source separation for real-time decoding of motor unit activity in humans
被引:1
作者:
Rossato, Julien
论文数: 0引用数: 0
h-index: 0
机构:
Nantes Univ, Lab Movement Interact Performance UR 4334, Nantes, FranceNantes Univ, Lab Movement Interact Performance UR 4334, Nantes, France
Rossato, Julien
[1
]
Hug, Francois
论文数: 0引用数: 0
h-index: 0
机构:
Univ Cote Azur, LAMHESS, Nice, France
Univ Queensland, Sch Biomed Sci, Brisbane, Qld, AustraliaNantes Univ, Lab Movement Interact Performance UR 4334, Nantes, France
Hug, Francois
[2
,3
]
Tucker, Kylie
论文数: 0引用数: 0
h-index: 0
机构:
Univ Queensland, Sch Biomed Sci, Brisbane, Qld, AustraliaNantes Univ, Lab Movement Interact Performance UR 4334, Nantes, France
Tucker, Kylie
[3
]
Gibbs, Ciara
论文数: 0引用数: 0
h-index: 0
机构:
Imperial Coll London, Fac Engn, Dept Bioengn, London, EnglandNantes Univ, Lab Movement Interact Performance UR 4334, Nantes, France
Gibbs, Ciara
[4
]
Lacourpaille, Lilian
论文数: 0引用数: 0
h-index: 0
机构:
Nantes Univ, Lab Movement Interact Performance UR 4334, Nantes, FranceNantes Univ, Lab Movement Interact Performance UR 4334, Nantes, France
Lacourpaille, Lilian
[1
]
Farina, Dario
论文数: 0引用数: 0
h-index: 0
机构:
Imperial Coll London, Fac Engn, Dept Bioengn, London, EnglandNantes Univ, Lab Movement Interact Performance UR 4334, Nantes, France
Farina, Dario
[4
]
Avrillon, Simon
论文数: 0引用数: 0
h-index: 0
机构:
Imperial Coll London, Fac Engn, Dept Bioengn, London, EnglandNantes Univ, Lab Movement Interact Performance UR 4334, Nantes, France
Avrillon, Simon
[4
]
机构:
[1] Nantes Univ, Lab Movement Interact Performance UR 4334, Nantes, France
[2] Univ Cote Azur, LAMHESS, Nice, France
[3] Univ Queensland, Sch Biomed Sci, Brisbane, Qld, Australia
[4] Imperial Coll London, Fac Engn, Dept Bioengn, London, England
来源:
ELIFE
|
2024年
/
12卷
基金:
欧洲研究理事会;
英国工程与自然科学研究理事会;
英国生物技术与生命科学研究理事会;
关键词:
electromyography;
motor unit;
decomposition;
neural decoding;
ACTION-POTENTIALS;
IDENTIFICATION;
PHYSIOLOGY;
D O I:
10.7554/eLife.88670
中图分类号:
Q [生物科学];
学科分类号:
07 ;
0710 ;
09 ;
摘要:
Decoding the activity of individual neural cells during natural behaviours allows neuroscientists to study how the nervous system generates and controls movements. Contrary to other neural cells, the activity of spinal motor neurons can be determined non-invasively (or minimally invasively) from the decomposition of electromyographic (EMG) signals into motor unit firing activities. For some interfacing and neuro-feedback investigations, EMG decomposition needs to be performed in real time. Here, we introduce an open-source software that performs real-time decoding of motor neurons using a blind-source separation approach for multichannel EMG signal processing. Separation vectors (motor unit filters) are optimised for each motor unit from baseline contractions and then re-applied in real time during test contractions. In this way, the firing activity of multiple motor neurons can be provided through different forms of visual feedback. We provide a complete framework with guidelines and examples of recordings to guide researchers who aim to study movement control at the motor neuron level. We first validated the software with synthetic EMG signals generated during a range of isometric contraction patterns. We then tested the software on data collected using either surface or intramuscular electrode arrays from five lower limb muscles (gastrocnemius lateralis and medialis, vastus lateralis and medialis, and tibialis anterior). We assessed how the muscle or variation of contraction intensity between the baseline contraction and the test contraction impacted the accuracy of the real-time decomposition. This open-source software provides a set of tools for neuroscientists to design experimental paradigms where participants can receive real-time feedback on the output of the spinal cord circuits.
机构:
Ottobock Prod SE & Co KGaA, Vienna, AustriaImperial Coll London, Dept Bioengn, London, England
Dietl, Hans
Graimann, Bernhard
论文数: 0引用数: 0
h-index: 0
机构:
Ottobock SE & Co KGaA, Duderstadt, GermanyImperial Coll London, Dept Bioengn, London, England
Graimann, Bernhard
Hargrove, Levi J.
论文数: 0引用数: 0
h-index: 0
机构:
Shirley Ryan AbilityLab, Ctr Bion Med, Chicago, IL USA
Northwestern Univ, Dept Phys Med & Rehabil, Chicago, IL 60611 USA
Northwestern Univ, Dept Biomed Engn, Chicago, IL 60611 USAImperial Coll London, Dept Bioengn, London, England
Hargrove, Levi J.
Hoffmann, Klaus-Peter
论文数: 0引用数: 0
h-index: 0
机构:
Fraunhofer Inst Biomed Tech, Dept Med Engn & Neuroprosthet, Sulzbach, GermanyImperial Coll London, Dept Bioengn, London, England
Hoffmann, Klaus-Peter
Huang, He
论文数: 0引用数: 0
h-index: 0
机构:
North Carolina State Univ, NCSU UNC Joint Dept Biomed Engn, Raleigh, NC USA
Univ N Carolina, Chapel Hill, NC 27515 USAImperial Coll London, Dept Bioengn, London, England
Huang, He
Ingvarsson, Thorvaldur
论文数: 0引用数: 0
h-index: 0
机构:
Ossur Iceland, Dept Res & Dev, Reykjavik, Iceland
Univ Iceland, Fac Med, Reykjavik, IcelandImperial Coll London, Dept Bioengn, London, England
机构:
Ossur Iceland, Dept Res & Dev, Reykjavik, IcelandImperial Coll London, Dept Bioengn, London, England
Kristjansson, Kristleifur
Kuiken, Todd
论文数: 0引用数: 0
h-index: 0
机构:
Shirley Ryan AbilityLab, Ctr Bion Med, Chicago, IL USA
Northwestern Univ, Dept Phys Med & Rehabil, Chicago, IL 60611 USA
Northwestern Univ, Dept Biomed Engn, Chicago, IL 60611 USAImperial Coll London, Dept Bioengn, London, England
Kuiken, Todd
Micera, Silvestro
论文数: 0引用数: 0
h-index: 0
机构:
Scuola Super Sant Anna, Biorobot Inst, Pontedera, Italy
Scuola Super Sant Anna, Dept Excellence Robot & AI, Pontedera, Italy
Ecole Polytech Fed Lausanne, Bertarelli Fdn Chair Translat NeuroEngn, Ctr Neuroprosthet, Lausanne, Switzerland
Ecole Polytech Fed Lausanne, Inst Bioengn, Sch Engn, Lausanne, SwitzerlandImperial Coll London, Dept Bioengn, London, England
Micera, Silvestro
论文数: 引用数:
h-index:
机构:
Stieglitz, Thomas
Sturma, Agnes
论文数: 0引用数: 0
h-index: 0
机构:
Imperial Coll London, Dept Bioengn, London, England
Med Univ Vienna, Dept Plast & Reconstruct Surg, Clin Lab Bion Extrem Reconstruct, Vienna, AustriaImperial Coll London, Dept Bioengn, London, England
Sturma, Agnes
Tyler, Dustin
论文数: 0引用数: 0
h-index: 0
机构:
Case Western Reserve Univ, Case Sch Engn, Cleveland, OH 44106 USA
Louis Stokes Vet Affairs Med Ctr, Cleveland, OH USAImperial Coll London, Dept Bioengn, London, England
Tyler, Dustin
Weir, Richard F. Ff
论文数: 0引用数: 0
h-index: 0
机构:
Univ Colorado Denver, Bioengn Dept, Biomechatron Dev Lab, Aurora, CO USA
VA Eastern Colorado Healthcare Syst, Aurora, CO USAImperial Coll London, Dept Bioengn, London, England
Weir, Richard F. Ff
Aszmann, Oskar C.
论文数: 0引用数: 0
h-index: 0
机构:
Med Univ Vienna, Dept Plast & Reconstruct Surg, Clin Lab Bion Extrem Reconstruct, Vienna, AustriaImperial Coll London, Dept Bioengn, London, England
机构:
Ottobock Prod SE & Co KGaA, Vienna, AustriaImperial Coll London, Dept Bioengn, London, England
Dietl, Hans
Graimann, Bernhard
论文数: 0引用数: 0
h-index: 0
机构:
Ottobock SE & Co KGaA, Duderstadt, GermanyImperial Coll London, Dept Bioengn, London, England
Graimann, Bernhard
Hargrove, Levi J.
论文数: 0引用数: 0
h-index: 0
机构:
Shirley Ryan AbilityLab, Ctr Bion Med, Chicago, IL USA
Northwestern Univ, Dept Phys Med & Rehabil, Chicago, IL 60611 USA
Northwestern Univ, Dept Biomed Engn, Chicago, IL 60611 USAImperial Coll London, Dept Bioengn, London, England
Hargrove, Levi J.
Hoffmann, Klaus-Peter
论文数: 0引用数: 0
h-index: 0
机构:
Fraunhofer Inst Biomed Tech, Dept Med Engn & Neuroprosthet, Sulzbach, GermanyImperial Coll London, Dept Bioengn, London, England
Hoffmann, Klaus-Peter
Huang, He
论文数: 0引用数: 0
h-index: 0
机构:
North Carolina State Univ, NCSU UNC Joint Dept Biomed Engn, Raleigh, NC USA
Univ N Carolina, Chapel Hill, NC 27515 USAImperial Coll London, Dept Bioengn, London, England
Huang, He
Ingvarsson, Thorvaldur
论文数: 0引用数: 0
h-index: 0
机构:
Ossur Iceland, Dept Res & Dev, Reykjavik, Iceland
Univ Iceland, Fac Med, Reykjavik, IcelandImperial Coll London, Dept Bioengn, London, England
机构:
Ossur Iceland, Dept Res & Dev, Reykjavik, IcelandImperial Coll London, Dept Bioengn, London, England
Kristjansson, Kristleifur
Kuiken, Todd
论文数: 0引用数: 0
h-index: 0
机构:
Shirley Ryan AbilityLab, Ctr Bion Med, Chicago, IL USA
Northwestern Univ, Dept Phys Med & Rehabil, Chicago, IL 60611 USA
Northwestern Univ, Dept Biomed Engn, Chicago, IL 60611 USAImperial Coll London, Dept Bioengn, London, England
Kuiken, Todd
Micera, Silvestro
论文数: 0引用数: 0
h-index: 0
机构:
Scuola Super Sant Anna, Biorobot Inst, Pontedera, Italy
Scuola Super Sant Anna, Dept Excellence Robot & AI, Pontedera, Italy
Ecole Polytech Fed Lausanne, Bertarelli Fdn Chair Translat NeuroEngn, Ctr Neuroprosthet, Lausanne, Switzerland
Ecole Polytech Fed Lausanne, Inst Bioengn, Sch Engn, Lausanne, SwitzerlandImperial Coll London, Dept Bioengn, London, England
Micera, Silvestro
论文数: 引用数:
h-index:
机构:
Stieglitz, Thomas
Sturma, Agnes
论文数: 0引用数: 0
h-index: 0
机构:
Imperial Coll London, Dept Bioengn, London, England
Med Univ Vienna, Dept Plast & Reconstruct Surg, Clin Lab Bion Extrem Reconstruct, Vienna, AustriaImperial Coll London, Dept Bioengn, London, England
Sturma, Agnes
Tyler, Dustin
论文数: 0引用数: 0
h-index: 0
机构:
Case Western Reserve Univ, Case Sch Engn, Cleveland, OH 44106 USA
Louis Stokes Vet Affairs Med Ctr, Cleveland, OH USAImperial Coll London, Dept Bioengn, London, England
Tyler, Dustin
Weir, Richard F. Ff
论文数: 0引用数: 0
h-index: 0
机构:
Univ Colorado Denver, Bioengn Dept, Biomechatron Dev Lab, Aurora, CO USA
VA Eastern Colorado Healthcare Syst, Aurora, CO USAImperial Coll London, Dept Bioengn, London, England
Weir, Richard F. Ff
Aszmann, Oskar C.
论文数: 0引用数: 0
h-index: 0
机构:
Med Univ Vienna, Dept Plast & Reconstruct Surg, Clin Lab Bion Extrem Reconstruct, Vienna, AustriaImperial Coll London, Dept Bioengn, London, England