Advanced 2D Nanomaterials for Phototheranostics of Breast Cancer: A Paradigm Shift

被引:1
作者
Parihar, Arpana [1 ]
Gaur, Kritika [2 ]
Sarbadhikary, Paromita [3 ]
机构
[1] All India Inst Med Sci Bhopal, Dept Translat Med, Bhopal 462020, Madhya Pradesh, India
[2] ICAR Indian Council Agr Res, Cent Sheep & wool Res Inst, Malpura 304501, Rajasthan, India
[3] Univ Johannesburg, Fac Hlth Sci, Laser Res Ctr, POB 17011, ZA-2028 Johannesburg, South Africa
来源
ADVANCED BIOLOGY | 2025年 / 9卷 / 01期
基金
英国医学研究理事会; 新加坡国家研究基金会;
关键词
2D nanomaterials; bioimaging; breast cancer; cancer theranostics; photodynamic therapy; photothermal therapy; REDUCED GRAPHENE OXIDE; GUIDED PHOTOTHERMAL THERAPY; PHOTODYNAMIC THERAPY; IN-VIVO; BLACK PHOSPHORUS; NANO-GRAPHENE; CELL-DEATH; BIOMEDICAL APPLICATIONS; PATIENT PREFERENCES; NANOGRAPHENE OXIDE;
D O I
10.1002/adbi.202400441
中图分类号
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号
0805 ; 080501 ; 080502 ;
摘要
Breast cancer is the leading cause of women's deaths and associated comorbidities. The advanced and targeted strategies against breast cancer have gained considerable attention due to their potential enhanced therapeutic efficacy over conventional therapies. In this context, phototherapies like photodynamic therapy (PDT) and photothermal therapy (PTT) have shown promise as an effective and alternative strategy due to reduced side effects, noninvasiveness, and spatiotemporal specificity. With the advent of nanotechnology, several types of nanomaterials that have shown excellent prospects in increasing the efficacy of photo therapies have been exploited in cancer treatment. In recent years, 2D nanomaterials have stood out promising because of their unique ultrathin planar structure, chemical, physical, tunable characteristics, and corresponding remarkable physiochemical/biological properties. In this review, the potential and the current status of several types of 2D nanomaterials such as graphene-based nanomaterials, Mxenes, Black phosphorous, and Transition Metal Dichalcogenides for photo/thermo and combination-based imaging and therapy of breast cancer have been discussed. The current challenges and prospects in terms of translational potential in future clinical oncology are highlighted.
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页数:24
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