What is the Optimal Treatment for this Rare Entity: A Pediatric Case with the Hyalinizing Clear Cell Carcinoma of the Nasopharynx

被引：0
作者：
Ataseven, Eda [1 ]
Goktepe, Sebnem Onen [2 ]
Turhal, Goksel [3 ]
Demir, Derya [4 ]
Kamer, Serra [5 ]
Kantar, Mehmet [1 ]
机构：
[1] Ege Univ, Fac Med, Dept Pediat Hematol & Oncol, Izmir, Turkiye
[2] Univ Hlth Sci Turkiye, Dr Behcet Uz Pediat Dis & Surg Training & Res Hosp, Clin Pediat Hematol & Oncol, Izmir, Turkiye
[3] Ege Univ, Fac Med, Dept Ear Nose Throat, Izmir, Turkiye
[4] Ege Univ, Dept Pathol, Fac Med, Izmir, Turkiye
[5] Ege Univ, Fac Med, Dept Radiat Oncol, Izmir, Turkiye
来源：
JOURNAL OF PEDIATRIC RESEARCH | 2025年 / 12卷 / 01期
关键词：
Hyalinizing clear cell carcinoma; nasopharynx; childhood; treatment; surgery; EWSR1; REARRANGEMENTS; SALIVARY-GLAND; CASE SERIES; FUSION;
D O I：
10.4274/jpr.galenos.2024.34467
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Hyalinizing clear cell carcinoma (HCCC) is a rare low-grade malignant tumorof the minor salivary glands of the head and neck. It can also arise in the nasopharynx in rare cases. Only a few cases of nasopharyngeal HCCC (NHCCC) have been reported in the literature, and most patients are in their sixth decade of life. Due to this disease's rarity, there is no consensus on its optimal treatment. Surgical excision is the mainstay of treatment. However, the role of postoperative radiotherapy is unknown. Herein, we report on a case of NHCCC in a 14-year-old female, treated successfully with sur-gical resection and adjuvant radiotherapy. This patient is the youngest case of NHCCC reported in the literature.
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页码：38 / 44
页数：7
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