FPIES - an unusual non-IgE-mediated food allergy. Overview and case studies

被引：0

作者：

Schmidt, H. ^{[1
]}

Adelsberger, D. ^{[2
]}

Bode, S. ^{[1
]}

机构：

[1] Univ Klinikum Ulm, Klin Kinder & Jugendmed, Ambulanz Kinderpneumol Allergol & Mukoviszidose, Eythstr 24, D-89075 Ulm, Germany

[2] Klinikum Oldenburg AoR, Univ Klin Kinder & Jugendmed, Klin Padiatr Pneumol & Allergol, Oldenburg, Germany

来源：

ALLERGOLOGIE | 2024年 / 47卷 / 10期

关键词：

non-IgE-mediated food allergy; food-induced enterocolitis syndrome (FPIES); acute FPIES; chronic FPIES; food challenge testing; INDUCED ENTEROCOLITIS SYNDROME; COWS MILK; DIAGNOSIS;

D O I：

10.5414/ALX02512

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Food protein-induced enterocolitis syndrome (FPIES) is a rare, non-IgE-mediated food allergy. It occurs most frequently in infants and young children, but adults can also be affected. Acute FPIES with severe vomiting 1 - 4 hours after eating and chronic FPIES with vomiting, diarrhea, and failure to thrive are distinguished and exemplified in two cases here. Pathophysiologically, a combination of immunological, microbial, and dysfunctional aspects is causative. The diagnosis is made by a detailed clinical history and can be confirmed by food challenges. Treatment consists of avoiding the triggering foods. The prognosis is good, and tolerance has usually developed by school age.

引用

页码：621 / 629

页数：9

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