Copper catalyzed C(sp3)-H/C(sp3)-H cross-coupling of arylacetic acid equivalents with methylarenes via α-carbonyl radicals

被引：0

作者：

Singh, Anupam Kumar ^{[1
,2
]}

Rahaman, Ajijur ^{[1
,2
]}

Patel, Upendra Kumar Brijmohan ^{[1
]}

Patel, Tulsi R. ^{[2
,3
]}

Bhai, Surjit ^{[2
,3
]}

Ganguly, Bishwajit ^{[2
,3
]}

Bhadra, Sukalyan ^{[1
,2
]}

机构：

[1] CSIR Cent Salt & Marine Chem Res Inst, Inorgan Mat & Catalysis Div, GB Marg, Bhavnagar 364002, Gujarat, India

[2] Acad Sci & Innovat Res AcSIR, Ghaziabad 201002, India

[3] CSIR Cent Salt & Marine Chem Res Inst, Analyt & Environm Sci Div & Centralized Instrument, GB Marg, Bhavnagar 364002, Gujarat, India

来源：

CHEMICAL COMMUNICATIONS | 2025年 / 61卷 / 14期

关键词：

BENZYLATION; TOLUENE; ACTIVATION; ESTERS;

D O I：

10.1039/d4cc06801g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Arylacetic acid equivalents bearing a pyridine group undergo C(sp3)-H/C(sp3)-H cross coupling with diverse methylarenes in the presence of a copper based catalyst system. The reaction proceeds via the formation of alpha-carbonyl radicals giving access to alpha,beta-diarylpropionic acids. Preliminary study suggests that the catalyst system is capable of transforming arylbenzyl ketones into 1,2,3-triaryl ketones.

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收藏

页码：2941 / 2944

页数：5

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