Structural characteristics, biological activities and market applications of Rehmannia Radix polysaccharides: A review

被引：1
作者：
Huang, Lin [1 ]
Zhang, Haibo [1 ]
Xia, Wenrui [2 ]
Yao, Nairong [2 ]
Xu, Runchun [1 ]
He, Yanan [1 ]
Yang, Qiyue [2 ]
机构：
[1] Chengdu Univ Tradit Chinese Med, State Key Lab Southwestern Chinese Med Resources, Chengdu 611137, Sichuan, Peoples R China
[2] Hosp Chengdu Univ Tradit Chinese Med, Chengdu 610075, Peoples R China
来源：
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | 2024年 / 282卷
基金：
中国国家自然科学基金;
关键词：
Rehmannia Radix polysaccharides; Structural characteristics; Structure-activity relationships; Biological activities; GLUTINOSA-POLYSACCHARIDE; IMMUNOMODULATORY ACTIVITIES; RETICULOENDOTHELIAL SYSTEM; BIOACTIVE POLYSACCHARIDES; DENDRITIC CELLS; EXTRACTION; ROOT; PROLIFERATION; HYPERGLYCEMIA; INFLAMMATION;
D O I：
10.1016/j.ijbiomac.2024.136554
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Rehmannia Radix Polysaccharides (RRPs) are biopolymers that are isolated and purified from the roots of Rehmannia glutinosa Libosch, which have attracted considerable attention because of their biological activities, such as anti-inflammatory, antioxidant, immunomodulatory, anti-tumor, hypoglycaemic etc. In this manuscript, the composition and structural characteristics of RRPs are reviewed. Moreover, the research progress on the conformational relationships and biological activities of RRPs is systematically summarized. Additionally, this manuscript also analyzes 155 patents using RRPs as the main raw materials to explore the status quo and bottleneck for the development and utilization of RRPs. In summary, this review not only provides a theoretical basis for future research on RRPs but also provides clear guidance for their market applications and innovation.
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页数：17
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