Initial Diagnosis and Treatment of Low-Risk Gestational Trophoblastic Neoplasia

被引:0
作者
Alimena, Stephanie [1 ,2 ,3 ]
Elias, Kevin M. [1 ,2 ,3 ]
Horowitz, Neil S. [1 ,2 ,3 ]
Berkowitz, Ross S. [1 ,2 ,3 ]
机构
[1] Brigham & Womens Hosp, Dept Obstet & Gynecol, Div Gynecol Oncol, Boston, MA 02115 USA
[2] Dana Farber Canc Inst, Boston, MA 02115 USA
[3] Harvard Med Sch, Boston, MA 02115 USA
关键词
Gestational trophoblastic neoplasia; Low risk; Chemotherapy; Methotrexate; Dactinomycin; Immunotherapy; Hysterectomy; Second dilation and curettage; ACTINOMYCIN-D; FOLINIC ACID; METHOTREXATE INFUSION; PULSE DACTINOMYCIN; PRIMARY THERAPY; DISEASE; CHEMOTHERAPY; MANAGEMENT; EXPERIENCE; RESISTANCE;
D O I
10.1016/j.hoc.2024.07.005
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Though low-risk GTN is a highly curable disease, due to strong productive research, we can continue to advance understanding of how to minimize relapses, lessen toxicity of treatment, and help women to maintain their quality of life and fertility after treatment for GTN.
引用
收藏
页码:1233 / 1244
页数:12
相关论文
共 56 条
  • [1] Abu-Rustum N., 2024, NCCN Clinical Practice Guidelines in Oncology
  • [2] Chemotherapy for resistant or recurrent gestational trophoblastic neoplasia
    Alazzam, Mo'iad
    Tidy, John
    Osborne, Raymond
    Coleman, Robert
    Hancock, Barry W.
    Lawrie, Theresa A.
    [J]. COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2012, (12):
  • [3] First line chemotherapy in low risk gestational trophoblastic neoplasia
    Alazzam, Mo'iad
    Tidy, John
    Hancock, Barry W.
    Osborne, Raymond
    [J]. COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2009, (01):
  • [4] Comparison of methotrexate, actinomycin D, and etoposide for treating low-risk gestational trophoblastic neoplasia
    Baptista, Angela M.
    Belfort, Paulo
    [J]. INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS, 2012, 119 (01) : 35 - 38
  • [5] Berkowitz R., Initial management of low-risk gestational trophoblastic neoplasia
  • [6] Berkowitz R., Gestational trophoblastic neoplasia: Epidemiology, clinical features, diagnosis, staging, and risk stratification
  • [7] METHOTREXATE INFUSION AND FOLINIC ACID IN THE PRIMARY THERAPY OF NONMETASTATIC GESTATIONAL TROPHOBLASTIC TUMORS
    BERKOWITZ, RS
    GOLDSTEIN, DP
    BERNSTEIN, MR
    [J]. GYNECOLOGIC ONCOLOGY, 1990, 36 (01) : 56 - 59
  • [8] 10-YEARS EXPERIENCE WITH METHOTREXATE AND FOLINIC ACID AS PRIMARY THERAPY FOR GESTATIONAL TROPHOBLASTIC DISEASE
    BERKOWITZ, RS
    GOLDSTEIN, DP
    BERNSTEIN, MR
    [J]. GYNECOLOGIC ONCOLOGY, 1986, 23 (01) : 111 - 118
  • [9] First-line hysterectomy for women with low-risk non-metastatic gestational trophoblastic neoplasia no longer wishing to conceive
    Bolze, Pierre-Adrien
    Mathe, Melodie
    Hajri, Touria
    You, Benoit
    Dabi, Yohann
    Schott, Anne-Marie
    Patrier, Sophie
    Massardier, Jerome
    Golfier, Francois
    [J]. GYNECOLOGIC ONCOLOGY, 2018, 150 (02) : 282 - 287
  • [10] PD-L1 Expression in Premalignant and Malignant Trophoblasts From Gestational Trophoblastic Diseases Is Ubiquitous and Independent of Clinical Outcomes
    Bolze, Pierre-Adrien
    Patrier, Sophie
    Massardier, Jerome
    Hajri, Touria
    Abbas, Fatima
    Schott, Anne Marie
    Allias, Fabienne
    Devouassoux-Shisheboran, Mojgan
    Freyer, Gilles
    Golfier, Francois
    You, Benoit
    [J]. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2017, 27 (03) : 554 - 561