STK11 Adnexal Tumor: Exploring the Association With Peutz-Jeghers Syndrome and its Distinction From Morphologic Mimickers

被引：2
作者：
Bennett, Jennifer A. [1 ]
Oliva, Esther [2 ]
机构：
[1] Univ Chicago, Dept Pathol, 5841 S Maryland Ave,MC 6101, Chicago, IL 60637 USA
[2] Massachusetts Gen Hosp, Dept Pathol, Boston, MA USA
来源：
ADVANCES IN ANATOMIC PATHOLOGY | 2025年 / 32卷 / 01期
关键词：
Peutz-Jeghers syndrome; STK11 adnexal tumor; FATWO; mesonephric-like adenocarcinoma; mesothelioma; sex cord-stromal tumor; endometrioid carcinoma; PROBABLE WOLFFIAN ORIGIN; SEX CORD TUMOR; FEMALE GENITAL-TRACT; SERTOLI-CELL TUMOR; ANNULAR TUBULES; MUCINOUS METAPLASIA; ADENOMA MALIGNUM; STROMAL TUMORS; FALLOPIAN-TUBE; ENDOCERVICAL ADENOCARCINOMAS;
D O I：
10.1097/PAP.0000000000000460
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
STK11 adnexal tumor is a novel malignant neoplasm of uncertain histogenesis frequently arising in a para-adnexal location and associated with Peutz-Jeghers syndrome in similar to 50% of patients. Its broad morphologic spectrum and nonspecific immunohistochemical profile has resulted in misclassification in the past as a variety of other neoplasms including those of wolffian, sex cord-stromal, mesothelial, and epithelial derivation. This review focuses on the spectrum of adnexal neoplasms that may develop in Peutz-Jeghers syndrome, with particular emphasis on STK11 adnexal tumor and its differential diagnosis.
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页码：98 / 108
页数：11
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