STK11 Adnexal Tumor: Exploring the Association With Peutz-Jeghers Syndrome and its Distinction From Morphologic Mimickers

被引：2
作者：
Bennett, Jennifer A. [1 ]
Oliva, Esther [2 ]
机构：
[1] Univ Chicago, Dept Pathol, 5841 S Maryland Ave,MC 6101, Chicago, IL 60637 USA
[2] Massachusetts Gen Hosp, Dept Pathol, Boston, MA USA
来源：
ADVANCES IN ANATOMIC PATHOLOGY | 2025年 / 32卷 / 01期
关键词：
Peutz-Jeghers syndrome; STK11 adnexal tumor; FATWO; mesonephric-like adenocarcinoma; mesothelioma; sex cord-stromal tumor; endometrioid carcinoma; PROBABLE WOLFFIAN ORIGIN; SEX CORD TUMOR; FEMALE GENITAL-TRACT; SERTOLI-CELL TUMOR; ANNULAR TUBULES; MUCINOUS METAPLASIA; ADENOMA MALIGNUM; STROMAL TUMORS; FALLOPIAN-TUBE; ENDOCERVICAL ADENOCARCINOMAS;
D O I：
10.1097/PAP.0000000000000460
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
STK11 adnexal tumor is a novel malignant neoplasm of uncertain histogenesis frequently arising in a para-adnexal location and associated with Peutz-Jeghers syndrome in similar to 50% of patients. Its broad morphologic spectrum and nonspecific immunohistochemical profile has resulted in misclassification in the past as a variety of other neoplasms including those of wolffian, sex cord-stromal, mesothelial, and epithelial derivation. This review focuses on the spectrum of adnexal neoplasms that may develop in Peutz-Jeghers syndrome, with particular emphasis on STK11 adnexal tumor and its differential diagnosis.
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页码：98 / 108
页数：11
相关论文
共 94 条
  • [11] Recurrent and metastatic female adnexal tumor of probable Wolffian origin A case report and review of the literature
    Chen, Qiuhe
    Shen, Yangmei
    Xie, Chuan
    [J]. MEDICINE, 2021, 100 (13) : E25377
  • [12] Solid papillary mesothelial tumor
    Churg, Andrew
    Le Stang, Nolwenn
    Dacic, Sanja
    Pissaloux, Daniel
    Begueret, Hugues
    Dartigues, Peggy
    Giusiano-Courcambeck, Sophie
    Sequeiros, Ruth
    Pairon, Jean-Claude
    Tirode, Franck
    Galateau-Salle, Francoise
    [J]. MODERN PATHOLOGY, 2022, 35 (01) : 69 - 76
  • [13] Mesonephric and mesonephric-like carcinomas of the female genital tract: molecular characterization including cases with mixed histology and matched metastases
    da Silva, Edaise M.
    Fix, Daniel J.
    Sebastiao, Ana Paula Martins
    Selenica, Pier
    Ferrando, Lorenzo
    Kim, Sarah H.
    Stylianou, Anthe
    Da Cruz Paula, Arnaud
    Pareja, Fresia
    Smith, Evan S.
    Zehir, Ahmet
    Konner, Jason A.
    Cadoo, Karen
    Reis-Filho, Jorge S.
    Abu-Rustum, Nadeem R.
    Mueller, Jennifer J.
    Weigelt, Britta
    Park, Kay J.
    [J]. MODERN PATHOLOGY, 2021, 34 (08) : 1570 - 1587
  • [14] DAYA D, 1994, ARCH PATHOL LAB MED, V118, P310
  • [15] ENDOMETRIOID CARCINOMA OF THE FALLOPIAN-TUBE RESEMBLING AN ADNEXAL TUMOR OF PROBABLE WOLFFIAN ORIGIN - A REPORT OF 6 CASES
    DAYA, D
    YOUNG, RH
    SCULLY, RE
    [J]. INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY, 1992, 11 (02) : 122 - 130
  • [16] Dehghani A, 2023, LAB INVEST, V103, pS886
  • [17] Extrauterine Mesonephric-like Neoplasms Expanding the Morphologic Spectrum
    Deolet, Ellen
    Arora, Iteeka
    Van Dorpe, Jo
    van der Meulen, Joni
    Desai, Sudha
    Van Roy, Nadine
    Kaur, Baljeet
    van de Vijver, Koen
    McCluggage, W. Glenn
    [J]. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2022, 46 (01) : 124 - 133
  • [18] Sclerosis in Sex Cord-Stromal Tumors Other Than the Sclerosing Stromal Tumor A Report of 70 Cases
    Devins, Kyle M.
    Young, Robert H.
    [J]. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2023, 47 (07) : 774 - 784
  • [19] Wolffian adnexal tumor, so-called female adnexal tumor of probable wolffian origin (FATWO): Immunohistochemical evidence in support of a wolffian origin
    Devouassoux-Shisheboran, M
    Silver, SA
    Tavassoli, FA
    [J]. HUMAN PATHOLOGY, 1999, 30 (07) : 856 - 863
  • [20] Synchronous and metachronous endocervical and ovarian neoplasms - Evidence supporting interpretation of the ovarian neoplasms as metastatic endocervical adenocarcinomas simulating primary ovarian surface epithelial neoplasms
    Elishaev, E
    Gilks, CB
    Miller, D
    Srodon, M
    Kurman, RJ
    Ronnett, BM
    [J]. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2005, 29 (03) : 281 - 294
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