Unraveling host genetics and microbiome genome crosstalk: a novel therapeutic approach

被引:1
|
作者
Zhang, Qian [1 ]
Schwarz, Dennis [1 ,2 ]
Cheng, Yumei [3 ]
Sohrabi, Yahya [1 ,4 ]
机构
[1] Westfal Wilhelms Univ, Univ Hosp Munster, Dept Cardiol I Coronary & Peripheral Vasc Dis, Munster, Germany
[2] Westfal Wilhelms Univ, Univ Hosp Munster, Ctr Mol Biol Inflammat ZMBE, Inst Expt Pathol ExPat, Munster, Germany
[3] Guizhou Med Univ, Affiliated Hosp, Dept Crit Care Med, Guiyang, Guizhou, Peoples R China
[4] Charles Univ Prague, Fac Med 3, Dept Med Genet, Prague, Czech Republic
关键词
D O I
10.1016/j.molmed.2024.06.007
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The ability of the gut microbiome to adapt to a new environment and utilize a new metabolite or dietary compound by inducing structural variations (SVs) in the genome has an important role in human health. Here, we discuss recent data on host genetic regulation of SV induction and its use as a new therapeutic approach.
引用
收藏
页码:1007 / 1009
页数:3
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