Prepregnancy and Gestational Interventions to Prevent Childhood Obesity

被引:2
作者
Kampmann, Ulla [1 ,2 ]
Suder, Louise Birk [1 ,2 ]
Nygaard, Malene [3 ]
Geiker, Nina Rica Wium [4 ]
Nielsen, Henriette Svarre [5 ,6 ]
Almstrup, Kristian [7 ,8 ]
Bruun, Jens Meldgaard [1 ,2 ]
Magkos, Faidon [3 ]
Ovesen, Per [2 ,9 ]
Catalano, Patrick [10 ]
机构
[1] Aarhus Univ Hosp, Steno Diabet Ctr Aarhus, DK-8200 Aarhus, Denmark
[2] Aarhus Univ, Dept Clin Med, DK-8200 Aarhus, Denmark
[3] Univ Copenhagen, Dept Nutr Exercise & Sports, DK-1958 Frederiksberg C, Denmark
[4] Ctr Childhood Hlth, DK-2300 Copenhagen S, Denmark
[5] Copenhagen Univ Hosp Hvidovre, Dept Gynecol & Obstet, DK-2650 Hvidovre, Denmark
[6] Univ Copenhagen, Dept Clin Med, DK-2200 Copenhagen, Denmark
[7] Copenhagen Univ Hosp, Dept Growth & Reprod, Rigshosp, DK-2100 Copenhagen, Denmark
[8] Univ Copenhagen, Dept Cellular & Mol Med, DK-2200 Copenhagen, Denmark
[9] Aarhus Univ Hosp, Dept Gynecol & Obstet, DK-8200 Aarhus N, Denmark
[10] Harvard Med Sch, Massachusetts Gen Hosp, Div Reprod Endocrinol, Boston, MA 02114 USA
关键词
childhood obesity; prepregnancy interventions; gestational diabetes; metabolic health; lifestyle interventions; GLYCEMIC-INDEX DIET; BODY-MASS INDEX; RANDOMIZED CONTROLLED-TRIAL; ADVERSE PREGNANCY OUTCOMES; LIFE-STYLE INTERVENTION; HIGH-FAT DIET; WEIGHT-GAIN; BARIATRIC SURGERY; PHYSICAL-ACTIVITY; LONGITUDINAL CHANGES;
D O I
10.1210/clinem/dgae724
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Childhood obesity is a significant global health issue with complex and multifactorial origins, often beginning before conception and influenced by both maternal and paternal health. The increased prevalence of prepregnancy obesity and gestational diabetes mellitus in women of reproductive age contributes to a heightened risk of metabolic dysfunction in offspring. Current clinical practices often implement lifestyle interventions after the first trimester and have limited success, implying that they miss a critical window for effective metabolic adjustments. This review examines the limitations of lifestyle interventions during pregnancy in improving perinatal outcomes and highlights the importance of initiating such interventions before conception to positively impact parental health and fetal development. A re-evaluation of strategies is needed to enhance the metabolic health of prospective parents as a preventive measure against childhood obesity.
引用
收藏
页码:e8 / e18
页数:11
相关论文
共 135 条
[51]   Body mass index in relation to semen quality and reproductive hormones among 1,558 Danish men [J].
Jensen, TK ;
Andersson, AM ;
Jorgensen, N ;
Andersen, AG ;
Carlsen, E ;
Petersen, JH ;
Skakkebæk, NE .
FERTILITY AND STERILITY, 2004, 82 (04) :863-870
[52]   Effect of weight loss before in vitro fertilization in women with obesity or overweight and infertility: a systematic review and meta-analysis [J].
Jeong, Hye Gyeong ;
Cho, Sumin ;
Ryu, Ki-Jin ;
Kim, Tak ;
Park, Hyuntae .
SCIENTIFIC REPORTS, 2024, 14 (01)
[53]   Physical exercise during pregnancy and fetal growth measures: a study within the Danish National Birth Cohort [J].
Juhl, Mette ;
Olsen, Jorn ;
Andersen, Per Kragh ;
Nohr, Ellen Aagaard ;
Andersen, Anne-Marie Nybo .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2010, 202 (01) :63.e1-63.e8
[54]   Possible fetal determinants of male infertility (vol 10, pg 553, 2014) [J].
Juul, Anders ;
Almstrup, Kristian ;
Andersson, Anna-Maria ;
Jensen, Tina K. ;
Jorgensen, Niels ;
Main, Katharina M. ;
Rajpert-De Meyts, Ewa ;
Toppari, Jorma ;
Skakkebk, Niels E. .
NATURE REVIEWS ENDOCRINOLOGY, 2014, 10 (09) :553-562
[55]   Adipose tissue inflammation and metabolic dysfunction in obesity [J].
Kawai, Tatsuo ;
Autieri, Michael, V ;
Scalia, Rosario .
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2021, 320 (03) :C375-C391
[56]   Placental function in maternal obesity [J].
Kelly, Amy C. ;
Powell, Theresa L. ;
Jansson, Thomas .
CLINICAL SCIENCE, 2020, 134 (08) :961-984
[57]   Male obesity impacts DNA methylation reprogramming in sperm [J].
Keyhan, Sanaz ;
Burke, Emily ;
Schrott, Rose ;
Huang, Zhiqing ;
Grenier, Carole ;
Price, Thomas ;
Raburn, Doug ;
Corcoran, David L. ;
Soubry, Adelheid ;
Hoyo, Catherine ;
Murphy, Susan K. .
CLINICAL EPIGENETICS, 2021, 13 (01)
[58]   Cumulative live birth rates after weight reduction in obese women scheduled for IVF: follow-up of a randomized controlled trial [J].
Kluge, L. ;
Bergh, C. ;
Einarsson, S. ;
Pinborg, A. ;
Englund, A-L Mikkelsen ;
Thurin-Kjellberg, A. .
HUMAN REPRODUCTION OPEN, 2019, 2019 (04)
[59]   Maternal dietary glycaemic load during pregnancy and gestational weight gain, birth weight and postpartum weight retention: a study within the Danish National Birth Cohort [J].
Knudsen, Vibeke K. ;
Heitmann, Berit L. ;
Halldorsson, Thorhallur I. ;
Sorensen, Thorkild I. A. ;
Olsen, Sjurdur F. .
BRITISH JOURNAL OF NUTRITION, 2013, 109 (08) :1471-1478
[60]   Obesity as a medical problem [J].
Kopelman, PG .
NATURE, 2000, 404 (6778) :635-643