Prepregnancy and Gestational Interventions to Prevent Childhood Obesity

被引:2
作者
Kampmann, Ulla [1 ,2 ]
Suder, Louise Birk [1 ,2 ]
Nygaard, Malene [3 ]
Geiker, Nina Rica Wium [4 ]
Nielsen, Henriette Svarre [5 ,6 ]
Almstrup, Kristian [7 ,8 ]
Bruun, Jens Meldgaard [1 ,2 ]
Magkos, Faidon [3 ]
Ovesen, Per [2 ,9 ]
Catalano, Patrick [10 ]
机构
[1] Aarhus Univ Hosp, Steno Diabet Ctr Aarhus, DK-8200 Aarhus, Denmark
[2] Aarhus Univ, Dept Clin Med, DK-8200 Aarhus, Denmark
[3] Univ Copenhagen, Dept Nutr Exercise & Sports, DK-1958 Frederiksberg C, Denmark
[4] Ctr Childhood Hlth, DK-2300 Copenhagen S, Denmark
[5] Copenhagen Univ Hosp Hvidovre, Dept Gynecol & Obstet, DK-2650 Hvidovre, Denmark
[6] Univ Copenhagen, Dept Clin Med, DK-2200 Copenhagen, Denmark
[7] Copenhagen Univ Hosp, Dept Growth & Reprod, Rigshosp, DK-2100 Copenhagen, Denmark
[8] Univ Copenhagen, Dept Cellular & Mol Med, DK-2200 Copenhagen, Denmark
[9] Aarhus Univ Hosp, Dept Gynecol & Obstet, DK-8200 Aarhus N, Denmark
[10] Harvard Med Sch, Massachusetts Gen Hosp, Div Reprod Endocrinol, Boston, MA 02114 USA
关键词
childhood obesity; prepregnancy interventions; gestational diabetes; metabolic health; lifestyle interventions; GLYCEMIC-INDEX DIET; BODY-MASS INDEX; RANDOMIZED CONTROLLED-TRIAL; ADVERSE PREGNANCY OUTCOMES; LIFE-STYLE INTERVENTION; HIGH-FAT DIET; WEIGHT-GAIN; BARIATRIC SURGERY; PHYSICAL-ACTIVITY; LONGITUDINAL CHANGES;
D O I
10.1210/clinem/dgae724
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Childhood obesity is a significant global health issue with complex and multifactorial origins, often beginning before conception and influenced by both maternal and paternal health. The increased prevalence of prepregnancy obesity and gestational diabetes mellitus in women of reproductive age contributes to a heightened risk of metabolic dysfunction in offspring. Current clinical practices often implement lifestyle interventions after the first trimester and have limited success, implying that they miss a critical window for effective metabolic adjustments. This review examines the limitations of lifestyle interventions during pregnancy in improving perinatal outcomes and highlights the importance of initiating such interventions before conception to positively impact parental health and fetal development. A re-evaluation of strategies is needed to enhance the metabolic health of prospective parents as a preventive measure against childhood obesity.
引用
收藏
页码:e8 / e18
页数:11
相关论文
共 135 条
[1]   Sperm count is increased by diet-induced weight loss and maintained by exercise or GLP-1 analogue treatment: a randomized controlled trial [J].
Andersen, Emil ;
Juhl, Christian R. ;
Kjoller, Emma T. ;
Lundgren, Julie R. ;
Janus, Charlotte ;
Dehestani, Yasmin ;
Saupstad, Marte ;
Ingerslev, Lars R. ;
Duun, Olivia M. ;
Jensen, Simon B. K. ;
Holst, Jens J. ;
Stallknecht, Bente M. ;
Madsbad, Sten ;
Torekov, Signe S. ;
Barres, Romain .
HUMAN REPRODUCTION, 2022, 37 (07) :1414-1422
[2]  
[Anonymous], 2018, Obstet Gynecol, V131, pe49, DOI 10.1097/AOG.0000000000002501
[3]  
[Anonymous], 2022, The World Obesity Atlas
[4]   High-fat diet reprograms the epigenome of rat spermatozoa and transgenerationally affects metabolism of the offspring [J].
Barbosa, Thais de Castro ;
Ingerslev, Lars R. ;
Alm, Petter S. ;
Versteyhe, Soetkin ;
Massart, Julie ;
Rasmussen, Morten ;
Donkin, Ida ;
Sjogren, Rasmus ;
Mudry, Jonathan M. ;
Vetterli, Laurene ;
Gupta, Shashank ;
Krook, Anna ;
Zierath, Juleen R. ;
Barres, Romain .
MOLECULAR METABOLISM, 2016, 5 (03) :184-197
[5]   The origins of the developmental origins theory [J].
Barker, D. J. P. .
JOURNAL OF INTERNAL MEDICINE, 2007, 261 (05) :412-417
[6]   Association between insulin sensitivity and lean mass loss during weight loss [J].
Bartholomew, Ciera L. ;
Martins, Catia ;
Gower, Barbara .
OBESITY, 2024, 32 (06) :1156-1162
[7]   Lifestyle Interventions to Improve Pregnancy Outcomes: a Systematic Review and Specified Meta-Analyses [J].
Behnam, Susann ;
Timmesfeld, Nina ;
Arabin, Birgit .
GEBURTSHILFE UND FRAUENHEILKUNDE, 2022, 82 (11) :1249-1264
[8]  
Bjerregaard LG, 2018, NEW ENGL J MED, V378, P1302, DOI [10.1056/NEJMoa1713231, 10.1056/nejmoa1713231]
[9]   Instrumental variable analysis using offspring BMI in childhood as an indicator of parental BMI in relation to mortality [J].
Blond, Kim ;
Carslake, David ;
Gjaerde, Line Klingen ;
Vistisen, Dorte ;
Sorensen, Thorkild I. A. ;
Smith, George Davey ;
Baker, Jennifer L. .
SCIENTIFIC REPORTS, 2021, 11 (01)
[10]   Effects of lifestyle intervention in obese pregnant women on gestational weight gain and mental health: a randomized controlled trial [J].
Bogaerts, A. F. L. ;
Devlieger, R. ;
Nuyts, E. ;
Witters, I. ;
Gyselaers, W. ;
van den Bergh, B. R. H. .
INTERNATIONAL JOURNAL OF OBESITY, 2013, 37 (06) :814-821